Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 14/20 | 0.47 |
| ▸ | CA2 | P00918 | 14/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tripamide SCHEMBL1651231 | 0.75 | KDM4E (0.59) | KDM4ELMNAGLAMAPTHTT | |
| Tripamide SCHEMBL49666 | 0.75 | KDM4E (0.59) | KDM4ELMNAGLAMAPTHTT | |
| SCHEMBL9352633 | 0.70 | CA1 (0.58) | KDM4ELMNAGLAMAPTHTT | |
| Clopamide SCHEMBL124598 | 0.69 | KDM4E (1.00) | KDM4ELMNAGLAMAPTHTT | |
| Clopamide SCHEMBL1650071 | 0.69 | KDM4E (1.00) | KDM4ELMNAGLAMAPTHTT | |
| SCHEMBL11883394 | 0.67 | LMNA (0.52) | KDM4ELMNAGLAMAPTHTT | |
| Zidapamide SCHEMBL2109204 | 0.66 | CA1 (0.63) | KDM4ELMNAGLAMAPTHTT | |
| SCHEMBL1272484 | 0.66 | CA1 (0.71) | CA1CA2 | |
| SCHEMBL31670530 | 0.65 | CNR2 (0.73) | KDM4ELMNAGLAMAPTHTT | |
| SCHEMBL13687260 | 0.65 | CA1 (0.66) | KDM4ELMNAGLAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184033-A1 | METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY | Lineage Cell Therapeutics, Inc. | 2010-07-22 | — | — | US | disclosed |
| US-20080226601-A1 | Herpes Virus-Based Compositions and Methods of Use in the Prenatal and Perinatal Periods | UNIVERSITY OF ROCHESTER (US) | 2008-09-18 | — | — | US | disclosed |