Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | GLA | P06280 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | CA1 | P00915 | 10/20 | 0.61 |
| ▸ | CA2 | P00918 | 10/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CA3 | P07451 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | CA4 | P22748 | 1/20 | 0.61 |
| ▸ | CA6 | P23280 | 1/20 | 0.61 |
| ▸ | CA5A | P35218 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | CA7 | P43166 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Clopamide SCHEMBL1650071 | 1.00 | KDM4E (1.00) | KDM4ELMNAGLAMAPTHTT | |
| SCHEMBL27462399 | 0.91 | LMNA (0.83) | KDM4ELMNAGLAMAPTHTT | |
| Clopamide SCHEMBL28278560 | 0.82 | LMNA (0.68) | KDM4ELMNAGLAMAPTHTT | |
| Clopamide SCHEMBL28086094 | 0.82 | LMNA (0.68) | KDM4ELMNAGLAMAPTHTT | |
| Clopamide SCHEMBL28086350 | 0.81 | MAPT (0.66) | KDM4ELMNAGLAMAPTHTT | |
| Cyclopenthiazide SCHEMBL28279853 | 0.79 | LMNA (0.66) | KDM4ELMNAGLAMAPTHTT | |
| SCHEMBL8971767 | 0.79 | LMNA (0.65) | KDM4ELMNAGLAMAPTHTT | |
| SCHEMBL31151392 | 0.79 | LMNA (0.65) | KDM4ELMNAGLAMAPTHTT | |
| Bumetanide SCHEMBL11583659 | 0.78 | KDM4E (0.66) | KDM4ELMNAGLAMAPTHTT | |
| Indapamide SCHEMBL476213 | 0.76 | CA1 (1.00) | KDM4ELMNAGLAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3017 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026090360-A1 | FUSED PYRIMIDINE COMPOUNDS FOR TREATMENT OF TINNITUS, HEARING LOSS, AND MENIERE'S DISEASE | OVID THERAPEUTICS INC. (US) | 2026-04-30 | — | — | WO | claimed |
| US-20260108529-A1 | FUSED AMINO PYRIMIDINE COMPOUNDS FOR TREATMENT OF TINNITUS, ACUTE SENSORINEURAL HEARING LOSS, AGE-RELATED HEARING LOSS, AND MENIERE'S DISEASE | OVID THERAPEUTICS INC (US) | 2026-04-23 | — | — | US | claimed |
| EP-4722714-A1 | SIMULTANEOUS ANALYSIS OF FOOD-BORNE DOPING SUBSTANCES USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (VFD: VACCINE FOR FOODBORNE DOPING) | Korea Institute of Science and Technology (KR) | 2026-04-08 | — | — | EP | claimed |
| US-20250057876-A1 | METHODS FOR TREATING AND/OR PREVENTING LYMPHANGIOGENESIS-ASSOCIATED DISEASES BY USING GOLD NANOCLUSTERS | GOLDRED NANOBIOTECH CO., LTD. (TW) | 2025-02-20 | — | — | US | claimed |
| US-20240226084-A9 | HIGH PENETRATION PRODRUG COMPOSITIONS AND PHARMACEUTICAL COMPOSITION THEREOF FOR TREATMENT OF PULMONARY CONDITIONS | TECHFIELDS PHARMA CO., LTD. (CN) | 2024-07-11 | — | — | US | claimed |
| US-20240131017-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS AND PHARMACEUTICAL COMPOSITION THEREOF FOR TREATMENT OF PULMONARY CONDITIONS | TECHFIELDS PHARMA CO., LTD. (CN) | 2024-04-25 | — | — | US | claimed |
| WO-2024085695-A1 | NOVEL ALTIRATINIB DERIVATIVE, MANUFACTURING METHOD THEREFOR, AND COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTION, ALLEVIATION, OR TREATMENT OF SKIN PIGMENTATION | 재단법인 아산사회복지재단 | 2024-04-25 | — | — | WO | claimed |
| US-20240115562-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS AND PHARMACEUTICAL COMPOSITION THEREOF FOR TREATMENT OF PULMONARY CONDITIONS | TECHFIELDS PHARMA CO., LTD. (CN) | 2024-04-11 | — | — | US | claimed |
| US-20240065979-A1 | Protection of Polyunsaturated Fatty Acids, Lipid-Soluble Vitamins, and Lipid-Soluble Medicaments from Oxidation | One Idea LLC (US) | 2024-02-29 | — | — | US | claimed |
| US-20230381161-A1 | COMPOSITIONS FOR THE TREATMENT OF HYPERTENSION | The George Institute for Global Health (AU) | 2023-11-30 | — | — | US | claimed |
| US-4557934-A | ALONG WITH A DIOL PYRROLIDONE OR AN AZACYCLOPENTAN-2-ONE | THE PROCTER & GAMBLE COMPANY (US) | 1985-12-10 | — | — | US | claimed |
| EP-0023355-B1 | MEDICINAL SOLUTIONS AND PROCESS FOR THEIR PREPARATION | Dr. Rentschler Arzneimittel GmbH & Co. (DE) | 1985-11-21 | — | — | EP | claimed |
| EP-0032725-B1 | NOVEL ALDEHYDE ADDUCTS OF TRIAMTERENE AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | MERCK & CO. INC. (US) | 1985-05-08 | — | — | EP | claimed |
| EP-0081157-B1 | PROCESS FOR THE PREPARATION OF N-NITROARYL-NITROARYL CARBOXAMIDES | BAYER AG (DE) | 1985-01-02 | — | — | EP | claimed |
| EP-0091385-A1 | Process for the preparation of p-hydroxybenzyl nitriles or p-hydroxybenzyl amines | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-10-12 | — | — | EP | claimed |
| EP-0019072-B1 | PENTADECAPEPTIDE, PROCESS FOR THE PREPARATION THEREOF AND IMMUNOPOTENTIATING AGENT | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-09-14 | — | — | EP | claimed |
| EP-0005825-B1 | ENERGY CONVERSION METHOD AND SYSTEM | Egosi, Dan (IL) | 1983-02-23 | — | — | EP | claimed |
| EP-0012000-B1 | PREVENTION OF DEPOSITS ON METAL SURFACES | DIAMOND SHAMROCK CORPORATION (US) | 1983-01-26 | — | — | EP | claimed |
| US-4285947-A | DIURETICS, HYPOTENSIVES | INTERX RESEARCH CORPORATION (US) | 1981-08-25 | — | — | US | claimed |
| EP-0032725-A1 | Novel aldehyde adducts of triamterene and a pharmaceutical composition containing the same | MERCK & CO. INC. (US) | 1981-07-29 | — | — | EP | claimed |