Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3500950 | 0.87 | MCL1 (0.60) | MCL1KDM4EALDH1A1KCNH2SMN1; SMN2 | |
| SCHEMBL3498475 | 0.87 | MCL1 (0.78) | MCL1KDM4EALDH1A1KCNH2SMN1; SMN2 | |
| SCHEMBL3501204 | 0.86 | MCL1 (0.58) | MCL1KDM4EALDH1A1KCNH2SMN1; SMN2 | |
| SCHEMBL3499722 | 0.81 | HIF1A (0.55) | MCL1KDM4EALDH1A1KCNH2SMN1; SMN2 | |
| SCHEMBL3498194 | 0.80 | MCL1 (0.40) | MCL1KDM4EALDH1A1CA12CA9 | |
| SCHEMBL3500040 | 0.78 | MCL1 (0.53) | MCL1KDM4ESMN1; SMN2LMNAMAPT | |
| SCHEMBL3498799 | 0.76 | MCL1 (0.51) | MCL1KDM4ESMN1; SMN2LMNAMAPT | |
| SCHEMBL3499014 | 0.75 | MCL1 (0.78) | MCL1KDM4EALDH1A1KCNH2SMN1; SMN2 | |
| SCHEMBL3498156 | 0.75 | MCL1 (0.49) | MCL1ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL3498797 | 0.75 | MCL1 (0.46) | MCL1KDM4EALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | GPR34, GPR4, GPR6 | MCL1 3727/4885KDM4E 2059/4885ALDH1A1 3047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.