Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4593962 | 0.79 | TLR8 (0.36) | ALDH1A1IDO1TDO2DCTPP1LMNA | |
| SCHEMBL27505488 | 0.78 | JAK2 (0.39) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL23722806 | 0.76 | TLR8 (0.36) | ALDH1A1CA2CYP3A4KDM4EMEN1 | |
| SCHEMBL27358659 | 0.71 | DPP4 (0.39) | ALDH1A1CA2CYP3A4KDM4EMEN1 | |
| SCHEMBL27636177 | 0.71 | DCTPP1 (0.41) | ALDH1A1CYP3A4KDM4EMEN1MAPT | |
| SCHEMBL450024 | 0.70 | ALDH1A1 (0.32) | ALDH1A1CA2CYP3A4KDM4EMEN1 | |
| SCHEMBL27658616 | 0.65 | CYP4Z1 (0.41) | ALDH1A1IDO1TDO2DCTPP1TLR8 | |
| SCHEMBL22343046 | 0.64 | ALDH1A1 (0.40) | ALDH1A1CA2CYP3A4KDM4EMEN1 | |
| O-Xylene SCHEMBL17007543 | 0.63 | ALDH1A1 (0.68) | ALDH1A1CA2CYP3A4KDM4EMEN1 | |
| SCHEMBL29367533 | 0.63 | GRM2 (0.41) | ALDH1A1KDM4EMEN1KMT2ATLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100009875-A1 | Liquid Additives for the Stabilization of Lubricant Compositions | CHEMTURA CORPORATION (US) | 2010-01-14 | — | — | US | disclosed |