SCHEMBL3501828

SCHEMBL3501828

Nc1nc2c(ncn2[C@@]2(Br)C[C@H](O)[C@@H](CO)O2)c(=O)[nH]1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.48
TK1 P04183 2/20 0.43
PNP P00491 3/20 0.43
BLM P54132 2/20 0.43
USP2 O75604 1/20 0.43
TSHR P16473 1/20 0.43
EDNRA P25101 1/20 0.43
HTR2A P28223 1/20 0.43
RECQL P46063 1/20 0.43
HBB P68871 1/20 0.43
HSD17B10 Q99714 1/20 0.43
XDH P47989 2/20 0.42
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
CYP3A4 P08684 1/20 0.41
NFKB1 P19838 1/20 0.41
VCP P55072 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27745728 0.87 ADORA3 (0.48) ADORA3TK1PNPBLMUSP2
SCHEMBL8490899 0.87 ADORA3 (0.48) ADORA3TK1PNPBLMUSP2
SCHEMBL442295 0.87 ADORA3 (0.48) ADORA3TK1PNPBLMUSP2
SCHEMBL28874867 0.86 ADORA3 (0.52) ADORA3TK1PNPBLMUSP2
SCHEMBL3148834 0.86 ADORA3 (0.48) ADORA3TK1PNPBLMUSP2
SCHEMBL30822753 0.86 ADORA3 (0.48) ADORA3TK1PNPBLMUSP2
SCHEMBL442605 0.86 ADORA3 (0.48) ADORA3TK1PNPBLMUSP2
SCHEMBL31392666 0.86 ADORA3 (0.48) ADORA3TK1PNPBLMUSP2
SCHEMBL9489893 0.86 ADORA3 (0.48) ADORA3TK1PNPBLMUSP2
SCHEMBL3503652 0.86 ADORA3 (0.48) ADORA3TK1PNPBLMUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7635467-B2 Mammalian multipotent stem cells and compositions, methods of preparation and methods of administration thereof THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2009-12-22 US claimed
US-7618621-B2 Mammalian multipotent neural stem cells and compositions, methods of preparation and methods of administration thereof THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2009-11-17 US claimed
CN-110114476-B Sequencing method based on single fluorescent dye 青岛华大智造科技有限责任公司 2024-04-23 CN disclosed
US-11466318-B2 Single fluorescent dye-based sequencing method EGI TECH (SHEN ZHEN) CO., LIMITED (CN) 2022-10-11 US disclosed
EP-3564387-A1 SINGLE FLUORESCENT DYE BASED SEQUENCING METHOD BGI Shenzhen (CN) 2019-11-06 EP disclosed
US-20190330693-A1 SINGLE FLUORESCENT DYE-BASED SEQUENCING METHOD Qingdao MGI Tech Co., Ltd. (CN) 2019-10-31 US disclosed
CN-110121562-A Method of producing a composite material 牛津纳米孔技术公司 2019-08-13 CN disclosed
US-9358234-B2 Mammalian multipotent stem cells and compositions, methods of preparation and methods of administration thereof THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2016-06-07 US disclosed
US-20140037589-A1 NOVEL MAMMALIAN MULTIPOTENT STEM CELLS AND COMPOSITIONS, METHODS OF PREPARATION AND METHODS OF ADMINISTRATION THEREOF THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2014-02-06 US disclosed
US-8192732-B2 Mammalian multipotent stem cells and compositions, methods of preparation and methods of administration thereof UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2012-06-05 US disclosed
US-20100183567-A1 Novel Mammalian Multipotent Stem Cells and Compositions, Methods of Preparation and Methods of Administration Thereof THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2010-07-22 US disclosed
US-7635467-B2 Mammalian multipotent stem cells and compositions, methods of preparation and methods of administration thereof THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2009-12-22 US disclosed
US-7618621-B2 Mammalian multipotent neural stem cells and compositions, methods of preparation and methods of administration thereof THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2009-11-17 US disclosed
EP-1471970-A4 NOVEL MAMMALIAN MULTIPOTENT STEM CELLS AND COMPOSITIONS, METHODS OF PREPARATION AND METHODS OF ADMINISTRATION THEREOF UNIV ILLINOIS (US) 2006-08-02 EP disclosed
EP-1471970-A2 NOVEL MAMMALIAN MULTIPOTENT STEM CELLS AND COMPOSITIONS, METHODS OF PREPARATION AND METHODS OF ADMINISTRATION THEREOF BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2004-11-03 EP disclosed
US-20030219898-A1 Novel mammalian multipotent stem cells and compositions, methods of preparation and methods of administration thereof NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-11-27 US disclosed
US-20030148513-A1 Novel mammalian multipotent neural stem cells and compositions, methods of preparation and methods of administration thereof BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, THE 2003-08-07 US disclosed
WO-2003060085-A2 MAMMALIAN NEURAL STEM CELLS, COMPOSITIONS AND USES THEREOF THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2003-07-24 WO disclosed
WO-2003059276-A2 NOVEL MAMMALIAN MULTIPOTENT STEM CELLS AND COMPOSITIONS, METHODS OF PREPARATION AND METHODS OF ADMINISTRATION THEREOF THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2003-07-24 WO disclosed