SCHEMBL442295

SCHEMBL442295

Nc1nc2c(ncn2[C@@]2(O)C[C@H](O)[C@@H](CO)O2)c(=O)[nH]1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.48
TK1 P04183 2/20 0.44
PNP P00491 3/20 0.43
BLM P54132 2/20 0.43
USP2 O75604 1/20 0.43
TSHR P16473 1/20 0.43
EDNRA P25101 1/20 0.43
HTR2A P28223 1/20 0.43
RECQL P46063 1/20 0.43
HBB P68871 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
CYP3A4 P08684 1/20 0.42
NFKB1 P19838 1/20 0.42
VCP P55072 1/20 0.42
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HIF1A Q16665 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27745728 1.00 ADORA3 (0.48) ADORA3TK1PNPBLMUSP2
SCHEMBL8490899 0.88 ADORA3 (0.48) ADORA3TK1PNPBLMUSP2
SCHEMBL30822753 0.87 ADORA3 (0.48) ADORA3TK1PNPBLMUSP2
SCHEMBL3501828 0.87 ADORA3 (0.48) ADORA3TK1PNPBLMUSP2
SCHEMBL28874867 0.87 ADORA3 (0.52) ADORA3TK1PNPBLMUSP2
SCHEMBL3148834 0.87 ADORA3 (0.48) ADORA3TK1PNPBLMUSP2
SCHEMBL442605 0.87 ADORA3 (0.48) ADORA3TK1PNPBLMUSP2
SCHEMBL31392666 0.87 ADORA3 (0.48) ADORA3TK1PNPBLMUSP2
SCHEMBL9489893 0.87 ADORA3 (0.48) ADORA3TK1PNPBLMUSP2
SCHEMBL3503652 0.87 ADORA3 (0.48) ADORA3TK1PNPBLMUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117203336-A Huntingtin (HTT) iRNA pharmaceutical compositions and methods of use thereof 阿尔尼拉姆医药品有限公司 2023-12-08 CN claimed
CN-114040768-A Application of inosine in tumor immunotherapy 免疫闪耀生物科技有限责任公司 2022-02-11 CN claimed
WO-2020197905-A1 USE OF INOSINE FOR CANCER IMMUNOTHERAPY IMMUNOSPARKLE BIOSCIENCE LLC (US) 2020-10-01 WO claimed
US-10736913-B1 Use of inosine for cancer immunotherapy IMMUNOSPARKLE BIOSCIENCE LLC (US) 2020-08-11 US claimed
EP-3111800-B1 DEVICE FOR IDENTIFYING ORAL CONDITIONS COLGATE PALMOLIVE CO (US) 2018-11-21 EP claimed
CN-104970898-B For identifying the device of oral conditions 高露洁-棕榄公司 2018-05-29 CN claimed
US-9700395-B2 Device for identifying oral conditions COLGATE-PALMOLIVE COMPANY (US) 2017-07-11 US claimed
EP-3111800-A1 DEVICE FOR IDENTIFYING ORAL CONDITIONS Colgate-Palmolive Company (US) 2017-01-04 EP claimed
CN-104970898-A DEVICE FOR IDENTIFYING ORAL CONDITIONS COLGATE PALMOLIVE CO 2015-10-14 CN claimed
US-20150072301-A1 DEVICE FOR IDENTIFYING ORAL CONDITIONS COLGATE PALMOLIVE CO (US) 2015-03-12 US claimed
US-20120322023-A1 DEVICE FOR IDENTIFYING ORAL CONDITIONS COLGATE-PALMOLIVE COMPANY (US) 2012-12-20 US claimed
CN-102655788-A Device for identifying oral conditions COLGATE PALMOLIVE CO 2012-09-05 CN claimed
CN-1188268-A Method for assessing oxidative stress and its control in humans NIKKON FOODS CO LTD (JP) 1998-07-22 CN claimed
EP-0845732-A2 Method for assessing oxidative stress and its control in humans Nikken Foods Company Limited (JP) 1998-06-03 EP claimed
US-12622640-B2 Oral data collecting device for diagnosis or prognosis Emanate Biomedical, Inc. (US) 2026-05-12 US disclosed
US-20260071179-A1 PRODUCTION METHOD OF NERVE CELLS DAMAGED BY OXIDATIVE STRESS AND APPLICATIONS THEREOF FUJIFILM CORPORATION (JP) 2026-03-12 US disclosed
EP-4682249-A1 METHOD FOR PRODUCING NERVE CELLS DAMAGED BY OXIDATION STRESS AND APPLICATION THEREOF FUJIFILM Corporation (JP) 2026-01-21 EP disclosed
US-5849782-A Methods of inhibiting neurodegenerative diseases THE GENERAL HOSPITAL CORPORATION (US) 1998-12-15 US disclosed
EP-0845732-A2 Method for assessing oxidative stress and its control in humans Nikken Foods Company Limited (JP) 1998-06-03 EP disclosed
WO-1996021445-A1 METHODS OF INHIBITING NEURODEGENERATIVE DISEASES THE GENERAL HOSPITAL CORPORATION (US) 1996-07-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10736913-B1 Use of inosine for cancer immunotherapy CD47, ICOS, HAVCR2 ADORA3 51/4885TK1 300/4885PNP 879/4885
US-12622640-B2 Oral data collecting device for diagnosis or prognosis TAS2R30, TAS2R39, TAS2R46 ADORA3 2450/4885TK1 903/4885PNP 3457/4885
US-20260071179-A1 PRODUCTION METHOD OF NERVE CELLS DAMAGED BY OXIDATIVE STRESS AND APPLICATIONS THEREOF AIFM2, AIFM1, FECH ADORA3 3143/4885TK1 3257/4885PNP 1179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.