SCHEMBL8490899

SCHEMBL8490899

Nc1nc2c(ncn2[C@@]2(N)C[C@H](O)[C@@H](CO)O2)c(=O)[nH]1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.48
TK1 P04183 2/20 0.45
PNP P00491 3/20 0.43
BLM P54132 2/20 0.43
USP2 O75604 1/20 0.43
TSHR P16473 1/20 0.43
EDNRA P25101 1/20 0.43
HTR2A P28223 1/20 0.43
RECQL P46063 1/20 0.43
HBB P68871 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
CYP3A4 P08684 1/20 0.42
NFKB1 P19838 1/20 0.42
VCP P55072 1/20 0.42
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HIF1A Q16665 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL442295 0.88 ADORA3 (0.48) ADORA3TK1PNPBLMUSP2
SCHEMBL27745728 0.88 ADORA3 (0.48) ADORA3TK1PNPBLMUSP2
SCHEMBL30822753 0.87 ADORA3 (0.48) ADORA3TK1PNPBLMUSP2
SCHEMBL3148834 0.87 ADORA3 (0.48) ADORA3TK1PNPBLMUSP2
SCHEMBL9489893 0.87 ADORA3 (0.48) ADORA3TK1PNPBLMUSP2
SCHEMBL3501828 0.87 ADORA3 (0.48) ADORA3TK1PNPBLMUSP2
SCHEMBL28874867 0.87 ADORA3 (0.52) ADORA3TK1PNPBLMUSP2
SCHEMBL442605 0.87 ADORA3 (0.48) ADORA3TK1PNPBLMUSP2
SCHEMBL31392666 0.87 ADORA3 (0.48) ADORA3TK1PNPBLMUSP2
SCHEMBL3503652 0.87 ADORA3 (0.48) ADORA3TK1PNPBLMUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025024123-A1 NOVEL CITICOLINE DERIVATIVES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-01-30 WO claimed
CN-120918189-B Application of small molecular compound in preventing and treating plant RNA virus infection 宁波大学 2026-04-28 CN disclosed
EP-4652277-A1 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF NEURODEGENERATIVE DISEASES Aptah Bio, Inc. (US) 2025-11-26 EP disclosed
EP-4652278-A1 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER Aptah Bio, Inc. (US) 2025-11-26 EP disclosed
CN-120918189-A Application of small molecular compound in preventing and treating plant RNA virus infection 宁波大学 2025-11-11 CN disclosed
WO-2025024123-A1 NOVEL CITICOLINE DERIVATIVES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-01-30 WO disclosed
WO-2024155740-A1 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER APTAH BIO, INC. (US) 2024-07-25 WO disclosed
WO-2024155739-A1 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF NEURODEGENERATIVE DISEASES APTAH BIO, INC. (US) 2024-07-25 WO disclosed
WO-2024137991-A2 ENGINEERED GUIDE RNAS AND POLYNUCLEOTIDES SHAPE THERAPEUTICS INC. (US) 2024-06-27 WO disclosed
CN-117751190-A Compositions and methods for modulating SOS gene expression 美国微哲默理有限责任公司 2024-03-22 CN disclosed
EP-4158018-A1 COMPOSITIONS AND METHODS FOR GENOME EDITING Shape Therapeutics Inc. (US) 2023-04-05 EP disclosed
WO-2022269346-A2 COMPOSITIONS AND METHODS OF MODULATING XANTHINE DEHYDROGENASE HORIZON THERAPEUTICS IRELAND DAC (IE) 2022-12-29 WO disclosed
CN-115023503-A Method for producing closed linear DNA 泰瑞斯疗法公司 2022-09-06 CN disclosed
CN-115003829-A Closed linear DNA with modified nucleotides 泰瑞斯疗法公司 2022-09-02 CN disclosed
WO-2022103839-A1 RNA EDITING COMPOSITIONS AND USES THEREOF SHAPE THERAPEUTICS INC. (US) 2022-05-19 WO disclosed
CN-114381470-A Artificial nucleic acid molecules 库瑞瓦格股份公司 2022-04-22 CN disclosed
EP-3108010-A1 SAMPLE PREPARATION METHOD Oxford Nanopore Technologies Limited (GB) 2016-12-28 EP disclosed
WO-2015124935-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2015-08-27 WO disclosed
WO-1999020753-A2 PEPTIDE BOND FORMATION USING NUCLEIC ACID CATALYSTS RIBOZYME PHARMACEUTICALS, INC. (US) 1999-04-29 WO disclosed
EP-0381335-A1 Antiviral agent and novel nucleoside TANABE SEIYAKU CO., LTD. (JP) 1990-08-08 EP disclosed