Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.60 |
| ▸ | POLB | P06746 | 4/20 | 0.60 |
| ▸ | USP2 | O75604 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 2/20 | 0.46 |
| ▸ | HBB | P68871 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3503153 | 0.89 | MEN1 (0.61) | MEN1KMT2APOLBUSP2ALDH1A1 | |
| SCHEMBL3503912 | 0.87 | MEN1 (0.69) | MEN1KMT2APOLBUSP2ALDH1A1 | |
| SCHEMBL3503519 | 0.85 | MEN1 (0.66) | MEN1KMT2APOLBUSP2ALDH1A1 | |
| SCHEMBL23373805 | 0.84 | MEN1 (0.64) | MEN1KMT2APOLBUSP2ALDH1A1 | |
| SCHEMBL16085240 | 0.81 | KEAP1 (0.60) | MEN1KMT2APOLBUSP2ALDH1A1 | |
| SCHEMBL10262050 | 0.81 | LMNA (0.59) | MEN1KMT2APOLBUSP2ALDH1A1 | |
| SCHEMBL10262375 | 0.81 | CYP1B1 (0.60) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL3504382 | 0.80 | MEN1 (0.69) | MEN1KMT2APOLBUSP2ALDH1A1 | |
| SCHEMBL31094030 | 0.80 | MEN1 (0.69) | MEN1KMT2APOLBUSP2ALDH1A1 | |
| SCHEMBL26053794 | 0.80 | MEN1 (0.69) | MEN1KMT2APOLBUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8440835-B2 | Environmentally sensitive fluorophores | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-05-14 | — | — | US | disclosed |
| US-8440835-B2 | Environmentally sensitive fluorophores | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-05-14 | — | — | US | disclosed |
| US-8440835-B2 | Environmentally sensitive fluorophores | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-05-14 | — | — | US | disclosed |
| US-20100168428-A1 | ENVIRONMENTALLY SENSITIVE FLUOROPHORES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-07-01 | — | — | US | disclosed |
| US-20100168428-A1 | ENVIRONMENTALLY SENSITIVE FLUOROPHORES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-07-01 | — | — | US | disclosed |
| US-20100168428-A1 | ENVIRONMENTALLY SENSITIVE FLUOROPHORES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-07-01 | — | — | US | disclosed |
| WO-2008106104-A2 | ENVIRONMENTALLY SENSITIVE FLUOROPHORES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-09-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168428-A1 | ENVIRONMENTALLY SENSITIVE FLUOROPHORES | PTMS, IK, PHAX | MEN1 3976/4885KMT2A 4753/4885POLB 4198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.