SCHEMBL3504366

SCHEMBL3504366

O=P(O)(O)OC[C@H]1O[C@H](OP(=O)(O[C@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O)OP(=O)(O[C@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O)O[C@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O)[C@H](O)[C@@H]1O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 2/20 0.66
IGF2R P11717 4/20 0.58
AMDHD2 Q9Y303 1/20 0.48
B4GALT1 P15291 1/20 0.39
P2RY14 Q15391 1/20 0.39
DNPH1 O43598 1/20 0.39
PRKAB2 O43741 1/20 0.39
TRPM2 O94759 1/20 0.39
LDHA P00338 1/20 0.39
ADRB2 P07550 1/20 0.39
SRC P12931 1/20 0.39
ADORA1 P30542 1/20 0.39
P2RY2 P41231 1/20 0.39
P2RY1 P47900 1/20 0.39
PRKAG1 P54619 1/20 0.39
PRKAA2 P54646 1/20 0.39
PDE4D Q08499 1/20 0.39
KCNH2 Q12809 1/20 0.39
PRKAA1 Q13131 1/20 0.39
PDE3A Q14432 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1332683 0.88 FBP1 (0.72) FBP1IGF2RAMDHD2DNPH1PRKAB2
SCHEMBL1702604 0.88 FBP1 (0.72) FBP1IGF2RAMDHD2DNPH1PRKAB2
SCHEMBL15344536 0.87 FBP1 (0.70) FBP1IGF2RAMDHD2B4GALT1P2RY14
SCHEMBL8847405 0.87 FBP1 (0.70) FBP1IGF2RAMDHD2B4GALT1P2RY14
SCHEMBL17072582 0.87 FBP1 (0.70) FBP1IGF2RAMDHD2B4GALT1P2RY14
SCHEMBL18710785 0.87 FBP1 (0.70) FBP1IGF2RAMDHD2B4GALT1P2RY14
SCHEMBL15341627 0.87 FBP1 (0.70) FBP1IGF2RAMDHD2B4GALT1P2RY14
SCHEMBL17070614 0.87 FBP1 (0.70) FBP1IGF2RAMDHD2B4GALT1P2RY14
SCHEMBL1266885 0.87 FBP1 (0.70) FBP1IGF2RAMDHD2B4GALT1P2RY14
SCHEMBL15333849 0.87 FBP1 (0.70) FBP1IGF2RAMDHD2B4GALT1P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2155879-B1 SYNTHESIS OF MYCOPHENOLIC ACID (MPA) DANMARKS TEKNISKE UNI TECHNICAL UNIVERSITY OF DENMARK (DK) 2015-04-01 EP disclosed
US-20130252290-A1 DNA ENCODING PROTEIN AND METHODS OF USING SAME DANMARKS TEKSNISKE UNIVERSITET (DK) 2013-09-26 US disclosed
US-8420378-B2 DNA encoding protein and methods of using same DANMARKS TEKNISKE UNIVERSITET (DK) 2013-04-16 US disclosed
US-20100190238-A1 SYNTHESIS OF MYCOPHENOLIC ACID (MPA) DANMARKS TEKNISKE UNIVERSITET (DK) 2010-07-29 US disclosed
EP-2155879-A1 SYNTHESIS OF MYCOPHENOLIC ACID (MPA) Danmarks Tekniske Universitet (Technical University of Denmark) (DK) 2010-02-24 EP disclosed
WO-2008151636-A1 SYNTHESIS OF MYCOPHENOLIC ACID (MPA) DANMARKS TEKNISKE UNIVERSITET (TECHNICAL UNIVERSITY OF DENMARK) (DK) 2008-12-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100190238-A1 SYNTHESIS OF MYCOPHENOLIC ACID (MPA) TPMT, FDPS, ME1 FBP1 111/4885IGF2R 560/4885AMDHD2 460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.