Oxyquinoline

Oxyquinoline

SCHEMBL350486

Oc1cccc2cccnc12.Oc1cccc2cccnc12.Oc1cccc2cccnc12.Oc1cccc2cccnc12.[Zr]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.95
MMP2 P08253 2/20 0.95
METAP2 P50579 2/20 0.95
CHRM1 P11229 1/20 0.95
COMT P21964 1/20 0.95
ADRA1A P35348 1/20 0.95
METAP1 P53582 1/20 0.95
HDAC8 Q9BY41 1/20 0.95
KDM4E B2RXH2 7/20 0.78
ALOX12 P18054 4/20 0.78
LMNA P02545 3/20 0.66
ALDH1A1 P00352 3/20 0.66
TDP1 Q9NUW8 3/20 0.58
MAPT P10636 2/20 0.58
TP53 P04637 2/20 0.58
ALOX15 P16050 2/20 0.58
HTT P42858 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
CYP3A4 P08684 2/20 0.58
HIF1A Q16665 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxyquinoline SCHEMBL5722126 1.00 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL73958 1.00 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL37189 0.98 TSHR (1.00) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL29365411 0.98 TSHR (1.00) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL29716519 0.98 TSHR (1.00) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL253313 0.98 TSHR (1.00) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL28199492 0.96 TSHR (0.88) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL23522696 0.95 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL22466317 0.95 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL21875199 0.95 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8932730-B2 Doped organic carrier transport materials The University of Northern California (US) 2015-01-13 US claimed
US-20050230665-A1 Doped organic carrier transport materials UNIVERSITY OF SOUTHERN CALIFORNIA, THE 2005-10-20 US claimed
WO-2003088271-A1 DOPED ORGANIC CARRIER TRANSPORT MATERIALS THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2003-10-23 WO claimed
US-11393998-B2 Doped organic carrier transport materials THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2022-07-19 US disclosed
CN-109153771-B Dihetero amines in conductive polymer compositions 株式会社LG化学 2022-04-12 CN disclosed
CN-109195970-B Electroactive material 株式会社LG 化学 2022-04-08 CN disclosed
CN-107250087-B Electroactive material 株式会社LG化学 2022-01-18 CN disclosed
CN-109153684-B Electroactive compounds 株式会社LG化学 2021-12-21 CN disclosed
CN-111386299-A Low color polymers for use in electronic devices E.I.内穆尔杜邦公司 2020-07-07 CN disclosed
US-20190312206-A1 DOPED ORGANIC CARRIER TRANSPORT MATERIALS UNIV SOUTHERN CALIFORNIA (US) 2019-10-10 US disclosed
US-10333070-B2 Doped organic carrier transport materials THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2019-06-25 US disclosed
WO-2007143201-A1 RED EMITTER COMPLEXES OF IR(III) AND DEVICES MADE WITH SUCH COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-12-13 WO disclosed
US-20070278936-A1 Red emitter complexes of IR(III) and devices made with such compounds E. I. DU PONT DE NEMOURS AND COMPANY 2007-12-06 US disclosed
EP-1859656-A2 ORGANOMETALLIC COMPLEXES E.I. du Pont de Nemours and Company (US) 2007-11-28 EP disclosed
EP-1834363-A2 ORGANOMETALLIC COMPLEXES E.I. DUPONT DE NEMOURS AND COMPANY (US) 2007-09-19 EP disclosed
WO-2007087223-A2 ORGANOMETALLIC COMPLEXES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-08-02 WO disclosed
WO-2006072015-A2 ORGANOMETALLIC COMPLEXES E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-07-06 WO disclosed
WO-2006072002-A2 ORGANOMETALLIC COMPLEXES E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-07-06 WO disclosed
US-20050230665-A1 Doped organic carrier transport materials UNIVERSITY OF SOUTHERN CALIFORNIA, THE 2005-10-20 US disclosed
WO-2003088271-A1 DOPED ORGANIC CARRIER TRANSPORT MATERIALS THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2003-10-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070278936-A1 Red emitter complexes of IR(III) and devices made with such compounds IK, TBL3, RTN3 TSHR 131/4885MMP2 4862/4885METAP2 4011/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.