Oxyquinoline

Oxyquinoline

SCHEMBL73958

Oc1cccc2cccnc12.[Zr]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.95
MMP2 P08253 2/20 0.95
METAP2 P50579 2/20 0.95
CHRM1 P11229 1/20 0.95
COMT P21964 1/20 0.95
ADRA1A P35348 1/20 0.95
METAP1 P53582 1/20 0.95
HDAC8 Q9BY41 1/20 0.95
KDM4E B2RXH2 7/20 0.78
ALOX12 P18054 4/20 0.78
LMNA P02545 3/20 0.66
ALDH1A1 P00352 3/20 0.66
TDP1 Q9NUW8 3/20 0.58
MAPT P10636 2/20 0.58
TP53 P04637 2/20 0.58
ALOX15 P16050 2/20 0.58
HTT P42858 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
CYP3A4 P08684 2/20 0.58
HIF1A Q16665 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxyquinoline SCHEMBL5722126 1.00 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL350486 1.00 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL37189 0.98 TSHR (1.00) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL29365411 0.98 TSHR (1.00) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL29716519 0.98 TSHR (1.00) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL253313 0.98 TSHR (1.00) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL28199492 0.96 TSHR (0.88) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL23522696 0.95 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL22466317 0.95 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL21875199 0.95 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1061 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105859792-A Electroluminescent metal complexes with dibenzo[f,h]quinoxalines 巴斯夫欧洲公司 2016-08-17 CN claimed
CN-101574017-B Phenanthroline compounds and electroluminescent devices using the same MERCK PATENT GMBH 2013-03-13 CN claimed
CN-101601329-B Electroluminescent device using azomethine-lithium-complex as electron injection layer MERCK PATENT GMBH 2012-07-11 CN claimed
CN-101601329-A Adopt the electroluminescent device of azomethine-lithium-complex as electron injecting layer MERCK PATENT GMBH (DE) 2009-12-09 CN claimed
CN-101574017-A Phenanthroline compounds and electroluminescent devices using the same OLED T LTD (DE) 2009-11-04 CN claimed
CN-101495596-A Electroluminescent device MERCK PATENT GMBH (DE) 2009-07-29 CN claimed
CN-101107884-A Electroluminescent materials and devices OLED T LTD (GB) 2008-01-16 CN claimed
US-6967062-B2 White light-emitting OLED device having a blue light-emitting layer doped with an electron-transporting or a hole-transporting material or both EASTMAN KODAK COMPANY (US) 2005-11-22 US claimed
WO-2005033246-A1 GREEN ORGANIC LIGHT-EMITTING DIODES EASTMAN KODAK COMPANY (US) 2005-04-14 WO claimed
US-20050058853-A1 Green organic light-emitting diodes EASTMAN KODAK COMPANY 2005-03-17 US claimed
US-20040185300-A1 White light-emitting OLED device having a blue light-emitting layer doped with an electron-transporting or a hole-transporting material or both EASTMAN KODAK COMPANY 2004-09-23 US claimed
CN-110891993-B Low temperature curing 1K basecoat and method for coating a substrate with a 1K basecoat 巴斯夫涂料有限公司 2022-11-22 CN disclosed
CN-110945085-B Low temperature cured coatings formed by polarity-promoted catalyst migration between layers in a two-layer cure mechanism 巴斯夫涂料有限公司 2022-07-12 CN disclosed
US-20220112222-A1 ZIRCONIUM-89 OXINE COMPLEX AS A CELL LABELING AGENT FOR POSITRON EMISSION TOMOGRAPHY THE UNITED STATES OF AMERICA,AS REPRESENTED BY THE SECRETARY,DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2022-04-14 US disclosed
CN-109153771-B Dihetero amines in conductive polymer compositions 株式会社LG化学 2022-04-12 CN disclosed
US-20030148208-A1 Apparatus for permitting transfer of organic material from a donor to form a layer in an OLED device EASTMAN KODAK COMPANY 2003-08-07 US disclosed
EP-1333510-A2 Using spacer elements to make electroluminescent display devices EASTMAN KODAK COMPANY (US) 2003-08-06 EP disclosed
EP-1321303-A1 Apparatus for transferring organic material from a donor to form a layer in an OLED device EASTMAN KODAK COMPANY (US) 2003-06-25 EP disclosed
CN-1424777-A Apparatus for transferring organic material by donor to form layer in organic LED device EASTMAN KODAK CO (US) 2003-06-18 CN disclosed
US-6565231-B1 OLED area illumination lighting apparatus EASTMAN KODAK COMPANY 2003-05-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220112222-A1 ZIRCONIUM-89 OXINE COMPLEX AS A CELL LABELING AGENT FOR POSITRON EMISSION TOMOGRAPHY OXTR, OXGR1, HCRTR2 TSHR 129/4885MMP2 2770/4885METAP2 3507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.