Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7265100 | 0.81 | ALDH1A1 (0.56) | ALDH1A1GAAKMT2AMEN1L3MBTL1 | |
| SCHEMBL7272751 | 0.81 | ALDH1A1 (0.56) | ALDH1A1GAAKMT2AMEN1L3MBTL1 | |
| SCHEMBL11360473 | 0.77 | ALDH1A1 (0.47) | ALDH1A1GAAKMT2AMEN1L3MBTL1 | |
| SCHEMBL7297775 | 0.76 | DNMT1 (0.65) | KMT2AMEN1L3MBTL1POLBKDM4E | |
| SCHEMBL7307301 | 0.75 | CYP2C19 (0.51) | ALDH1A1GAAKMT2AMEN1L3MBTL1 | |
| SCHEMBL29132823 | 0.74 | KDM4E (0.57) | ALDH1A1GAAKMT2AMEN1L3MBTL1 | |
| SCHEMBL30660068 | 0.74 | KDM4E (0.57) | ALDH1A1GAAKMT2AMEN1L3MBTL1 | |
| SCHEMBL29132822 | 0.74 | KDM4E (0.57) | ALDH1A1GAAKMT2AMEN1L3MBTL1 | |
| SCHEMBL2427953 | 0.74 | GAA (0.52) | ALDH1A1GAAKMT2AMEN1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL28479104 | 0.74 | CTSS (0.46) | ALDH1A1KMT2AMEN1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222546-A1 | METHODS FOR THE PREPARATION OF FUNCTIONALIZED PEPTIDES, PROTEINS AND CARBOHYDRATES AND THEIR CONJUGATES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222546-A1 | METHODS FOR THE PREPARATION OF FUNCTIONALIZED PEPTIDES, PROTEINS AND CARBOHYDRATES AND THEIR CONJUGATES | PTMS, STT3A, GCG | ALDH1A1 3690/4885GAA 1347/4885KMT2A 3803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.