1,6-Hexanediol

1,6-Hexanediol

SCHEMBL350585

O=C(O)C1=CO1.OCCCCCCO

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.42
FFAR1 O14842 1/20 0.42
FFAR4 Q5NUL3 1/20 0.42
KDM4E B2RXH2 7/20 0.36
CAMK2A Q9UQM7 1/20 0.35
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33
HTT P42858 1/20 0.32
KMT2A Q03164 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MAPK1 P28482 1/20 0.31
LMNA P02545 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
ALDH1A1 P00352 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MEN1 O00255 1/20 0.31
TSHR P16473 1/20 0.31
POLB P06746 1/20 0.31
GSTP1 P09211 2/20 0.30
GSTM2 P28161 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL83826 0.82
Acrylic Acid SCHEMBL1414471 0.72 LMNA (0.56) KDM4EKMT2ASMN1; SMN2MAPK1LMNA
Terephthalic Acid SCHEMBL6389843 0.70 TSHR (0.63) SMN1; SMN2ALDH1A1TSHR
Terephthalic Acid SCHEMBL11878692 0.70 TSHR (0.63) SMN1; SMN2ALDH1A1TSHR
1,6-Hexanediol SCHEMBL25434284 0.70 TDP1 (0.57) GPR84FFAR1FFAR4HTTKMT2A
1,6-Hexanediol SCHEMBL29109662 0.69 GPR84 (0.65) GPR84FFAR1FFAR4KDM4ECAMK2A
1,5-Pentanediol SCHEMBL575113 0.69 GPR84 (0.65) GPR84FFAR1FFAR4KDM4ECAMK2A
1,6-Hexanediol SCHEMBL628080 0.69 GPR84 (0.65) GPR84FFAR1FFAR4KDM4ECAMK2A
1,6-Hexanediol SCHEMBL28984424 0.69 GPR84 (0.65) GPR84FFAR1FFAR4KDM4ECAMK2A
1,6-Hexanediol SCHEMBL6707356 0.69 GPR84 (0.65) GPR84FFAR1FFAR4KDM4ECAMK2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120012366-A1 POLYAMIC ACID, POLYIMIDE, PHOTOSENSITIVE RESIN COMPOSITION COMPRISING THE SAME, AND DRY FILM MANUFACTURED FROM THE SAME LG CHEM, LTD. (KR) 2012-01-19 US disclosed
US-20110200939-A1 POLYAMIC ACID, POLYIMIDE, PHOTOSENSITIVE RESIN COMPOSITION COMPRISING THE SAME AND DRY FILM MANUFACTURED BY THE SAME LG CHEM, LTD. (KR) 2011-08-18 US disclosed
US-4843111-A PROTECTIVE COATINGS NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1989-06-27 US disclosed