⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10708212 | 0.96 | HIF1A (0.50) | — | |
| Hydrochloric Acid SCHEMBL20544691 | 0.96 | — | — | |
| SCHEMBL25633044 | 0.86 | — | — | |
| SCHEMBL19487323 | 0.84 | — | — | |
| SCHEMBL6578361 | 0.83 | CXCR4 (0.47) | — | |
| SCHEMBL29721488 | 0.83 | CXCR4 (0.47) | — | |
| SCHEMBL2193534 | 0.83 | CXCR4 (0.47) | — | |
| Thiomorpholine SCHEMBL93637 | 0.73 | HIF1A (0.42) | — | |
| Thiomorpholine SCHEMBL145846 | 0.73 | — | — | |
| SCHEMBL9873225 | 0.73 | HIF1A (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230173093-A1 | CHARGE VARIANT LINKERS | SEAGEN INC (US) | 2023-06-08 | — | — | US | disclosed |
| US-20230115413-A1 | Use of Thiol Compounds to Treat Neurological Disease | ZANKEL, TODD C, MR | 2023-04-13 | — | — | US | disclosed |
| EP-3614999-B1 | ODORLESS THIOLS FOR PERMANENT WAVING, STRAIGHTENING AND DEPILATORY APPLICATIONS | PROCTER & GAMBLE (US) | 2022-07-13 | — | — | EP | disclosed |
| US-20220040320-A1 | ADCS WITH THIOL MULTIPLEX LINKERS | SEAGEN INC. | 2022-02-10 | — | — | US | disclosed |
| EP-3897734-A1 | ADCS WITH THIOL MULTIPLEX LINKERS | Seagen Inc. (US) | 2021-10-27 | — | — | EP | disclosed |
| CN-113543812-A | ADC with sulfhydryl multiple linker | 西进公司 | 2021-10-22 | — | — | CN | disclosed |
| US-20210069129-A1 | Use of Thiol Compounds to Treat Neurological Disease | ZANKEL, TODD C, MR | 2021-03-11 | — | — | US | disclosed |
| WO-2020132655-A1 | ADCS WITH THIOL MULTIPLEX LINKERS | SEATTLE GENETICS, INC. (US) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020132655-A1 | ADCS WITH THIOL MULTIPLEX LINKERS | SEATTLE GENETICS, INC. (US) | 2020-06-25 | — | — | WO | disclosed |
| EP-2630494-B1 | METHOD FOR FUNCTIONALISING SURFACES FOR ANALYTE DETECTION | CENTRE NAT RECH SCIENT (FR) | 2020-03-18 | — | — | EP | disclosed |
| US-20120012472-A1 | NOVEL CHEMISTRY USED IN BIOSENSORS | OHMX CORPORATION (US) | 2012-01-19 | — | — | US | disclosed |
| WO-2011146143-A2 | DETECTION OF CANCER BY ASSAYING PSA ENZYMATIC ACTIVITY | OHMX CORPORATION (US) | 2011-11-24 | — | — | WO | disclosed |
| WO-2011051906-A1 | METHOD FOR NATIVE LIGATION OF POLYPEPTIDES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2011-05-05 | — | — | WO | disclosed |
| US-20110033869-A1 | Enzyme Triggered Redox Altering Chemical Elimination (E-Trace) Immunoassay | OHMX CORPORATION (US) | 2011-02-10 | — | — | US | disclosed |
| EP-2212342-A1 | ELECTROCHEMICAL ASSAY FOR THE DETECTION OF ENZYMES | Ohmx Corporation (US) | 2010-08-04 | — | — | EP | disclosed |
| EP-2210268-A1 | NOVEL CHEMISTRY USED IN BIOSENSORS | Ohmx Corporation (US) | 2010-07-28 | — | — | EP | disclosed |
| US-20100003710-A1 | Electrochemical Assay for the Detection of Enzymes | OHMX CORPORATION (US) | 2010-01-07 | — | — | US | disclosed |
| US-20090253149-A1 | Novel Chemistry Used in Biosensors | OHMX CORPORATION (US) | 2009-10-08 | — | — | US | disclosed |
| WO-2009052422-A1 | ELECTROCHEMICAL ASSAY FOR THE DETECTION OF ENZYMES | OHMX CORPORATION (US) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009052436-A1 | NOVEL CHEMISTRY USED IN BIOSENSORS | OHMX CORPORATION (US) | 2009-04-23 | — | — | WO | disclosed |