Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.55 |
| ▸ | CRHBP | P24387 | 2/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KDM4A | O75164 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18888546 | 0.87 | ALDH1A1 (0.54) | ALDH1A1POLBKCNQ2CRHBPCRHR2 | |
| SCHEMBL6937634 | 0.82 | ALDH1A1 (0.59) | ALDH1A1POLBKCNQ2CRHBPCRHR2 | |
| Phenobarbital SCHEMBL5886055 | 0.81 | MMP2 (0.49) | ALDH1A1POLBKCNQ2CRHBPCRHR2 | |
| Pheneturide SCHEMBL13724568 | 0.80 | SMN1; SMN2 (0.49) | ALDH1A1POLBKCNQ2CRHBPCRHR2 | |
| SCHEMBL2842510 | 0.80 | HDAC3 (0.63) | ALDH1A1POLBKCNQ2CRHBPCRHR2 | |
| SCHEMBL2049579 | 0.80 | ALDH1A1 (0.66) | ALDH1A1POLBKCNQ2CRHBPCRHR2 | |
| Acetylpheneturide SCHEMBL79701 | 0.80 | ALDH1A1 (0.54) | ALDH1A1POLBKCNQ2CRHBPCRHR2 | |
| Fenbutyramide SCHEMBL232920 | 0.80 | EPHX1 (0.63) | ALDH1A1POLBKCNQ2CRHBPCRHR2 | |
| Fenbutyramide SCHEMBL1478462 | 0.80 | EPHX1 (0.63) | ALDH1A1POLBKCNQ2CRHBPCRHR2 | |
| Fenbutyramide SCHEMBL1477997 | 0.80 | EPHX1 (0.63) | ALDH1A1POLBKCNQ2CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2524 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3607938-B1 | PHARMACEUTICAL COMPOSITION | SOVIC BRKICIC LJILJANA (HR) | 2026-05-27 | — | — | EP | claimed |
| EP-3518975-B1 | FORMULATION COMPRISING FENFLURAMINE AND CANNABIDIOL AND ITS USE IN THE TREATMENT OF SEIZURES | ZOGENIX INTERNATIONAL LTD (GB) | 2025-04-09 | — | — | EP | claimed |
| US-11878076-B2 | Lyophilized compositions of phenobarbital sodium salt | Nivagen Pharmaceuticals, Inc. (US) | 2024-01-23 | — | — | US | claimed |
| US-11786487-B2 | Formulation for inhibiting formation of 5-HT2B agonists and methods of using same | ZOGENIX INTERNATIONAL LIMITED (GB) | 2023-10-17 | — | — | US | claimed |
| WO-2023178250-A1 | TREATMENT OF TUBEROUS SCLEROSIS WITH MIRDAMETINIB | SpringWorks Therapeutics Inc. (US) | 2023-09-21 | — | — | WO | claimed |
| US-11759440-B2 | Formulation for inhibiting formation of 5-HT2B agonists and methods of using same | ZOGENIX INTERNATIONAL LIMITED (GB) | 2023-09-19 | — | — | US | claimed |
| US-20230157959-A1 | Lyophilized Compositions of Phenobarbital Sodium Salt | Nivagen Pharmaceuticals, Inc. (US) | 2023-05-25 | — | — | US | claimed |
| US-20220354794-A1 | Lyophilized Compositions of Phenobarbital Sodium Salt | Nivagen Pharmaceuticals, Inc. (US) | 2022-11-10 | — | — | US | claimed |
| US-11406598-B2 | Lyophilized compositions of phenobarbital sodium salt | Nivagen Pharmaceuticals, Inc. (US) | 2022-08-09 | — | — | US | claimed |
| US-20210393550-A1 | Formulation for Inhibiting Formation of 5-HT2B Agonists and Methods of Using Same | ZOGENIX INTERNATIONAL LIMITED (GB) | 2021-12-23 | — | — | US | claimed |
| CN-1829490-A | Films comprising therapeutic agents | TODD MAIBACH (US) | 2006-09-06 | — | — | CN | claimed |
| EP-1648362-A2 | FILM COMPRISING THERAPEUTIC AGENTS | Maibach, Todd (US) | 2006-04-26 | — | — | EP | claimed |
| US-20050070524-A1 | Compositions of a cyclooxygenase-2 selective inhibitor and an anticonvulsant agent for the treatment of central nervous system disorders | PHARMACIA CORPORATION | 2005-03-31 | — | — | US | claimed |
| WO-2005004989-A2 | FILM COMPRISING THERAPEUTIC AGENTS | MAIBACH TODD (US) | 2005-01-20 | — | — | WO | claimed |
| WO-2005000294-A1 | SELECTIVE INHIBITOR AND AN ANTICONVULSANT AGENT FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | PHARMACIA CORPORATION (US) | 2005-01-06 | — | — | WO | claimed |
| US-20040073280-A1 | Method of controlling body temperature while reducing shivering | RADIANT MEDICAL, INC. | 2004-04-15 | — | — | US | claimed |
| US-6702839-B1 | Method of controlling body temperature while reducing shivering | RADIANT MEDICAL, INC. | 2004-03-09 | — | — | US | claimed |
| CN-1294519-A | Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient | INPHARMA SA (CH) | 2001-05-09 | — | — | CN | claimed |
| EP-1073470-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2001-02-07 | — | — | EP | claimed |
| WO-2000048636-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2000-08-24 | — | — | WO | claimed |