SCHEMBL18888546

SCHEMBL18888546

CCC(C(=O)NC(=N)N)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.54
▸ POLB P06746 1/20 0.54
▸ KCNQ2 O43526 3/20 0.52
▸ CRHBP P24387 2/20 0.52
▸ CRHR2 Q13324 2/20 0.52
▸ LMNA P02545 1/20 0.52
▸ HTT P42858 1/20 0.52
▸ SMN1; SMN2 Q16637 1/20 0.52
▸ KDM4A O75164 1/20 0.51
▸ MAPT P10636 1/20 0.51
▸ MEN1 O00255 1/20 0.51
▸ KMT2A Q03164 1/20 0.51
▸ GAA P10253 1/20 0.50
▸ HDAC3 O15379 3/20 0.49
▸ HDAC4 P56524 3/20 0.49
▸ HDAC1 Q13547 3/20 0.49
▸ HDAC7 Q8WUI4 3/20 0.49
▸ HDAC2 Q92769 3/20 0.49
▸ HDAC10 Q969S8 3/20 0.49
▸ HDAC11 Q96DB2 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pheneturide SCHEMBL35066 0.87 ALDH1A1 (0.56) ALDH1A1POLBKCNQ2CRHBPCRHR2
SCHEMBL15553366 0.83 CRHBP (0.52) ALDH1A1POLBCRHBPCRHR2KDM4A
SCHEMBL15552462 0.83 CRHBP (0.52) ALDH1A1POLBCRHBPCRHR2KDM4A
Hydrochloric Acid SCHEMBL15559323 0.83 EPHX1 (0.41) ALDH1A1POLBKCNQ2CRHBPCRHR2
SCHEMBL15554309 0.83 CRHBP (0.52) ALDH1A1POLBCRHBPCRHR2KDM4A
SCHEMBL15553655 0.83 EPHX1 (0.63) ALDH1A1POLBHTTSMN1; SMN2KDM4A
SCHEMBL15555286 0.83 EPHX1 (0.63) ALDH1A1POLBHTTSMN1; SMN2KDM4A
SCHEMBL15554157 0.83 EPHX1 (0.63) ALDH1A1POLBHTTSMN1; SMN2KDM4A
Hydrochloric Acid SCHEMBL15559325 0.82 CRHBP (0.51) ALDH1A1POLBCRHBPCRHR2KDM4A
Hydrochloric Acid SCHEMBL15554159 0.81 EPHX1 (0.61) ALDH1A1POLBHTTSMN1; SMN2KDM4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240082161-A1 STABILIZATION OF PHENOBARBITAL SODIUM FOR INJECTION SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) 2024-03-14 — — US claimed
US-11878076-B2 Lyophilized compositions of phenobarbital sodium salt Nivagen Pharmaceuticals, Inc. (US) 2024-01-23 — — US claimed
US-11857683-B2 Stabilization of phenobarbital sodium for injection SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) 2024-01-02 — — US claimed
US-20230157959-A1 Lyophilized Compositions of Phenobarbital Sodium Salt Nivagen Pharmaceuticals, Inc. (US) 2023-05-25 — — US claimed
US-20230031957-A1 STABILIZATION OF PHENOBARBITAL SODIUM FOR INJECTION SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) 2023-02-02 — — US claimed
US-20220354794-A1 Lyophilized Compositions of Phenobarbital Sodium Salt Nivagen Pharmaceuticals, Inc. (US) 2022-11-10 — — US claimed
US-11406598-B2 Lyophilized compositions of phenobarbital sodium salt Nivagen Pharmaceuticals, Inc. (US) 2022-08-09 — — US claimed
US-20210085608-A1 Lyophilized Compositions of Phenobarbital Sodium Salt Nivagen Pharmaceuticals, Inc. (US) 2021-03-25 — — US claimed
US-20240082161-A1 STABILIZATION OF PHENOBARBITAL SODIUM FOR INJECTION SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) 2024-03-14 — — US disclosed
US-11878076-B2 Lyophilized compositions of phenobarbital sodium salt Nivagen Pharmaceuticals, Inc. (US) 2024-01-23 — — US disclosed
US-11878076-B2 Lyophilized compositions of phenobarbital sodium salt Nivagen Pharmaceuticals, Inc. (US) 2024-01-23 — — US disclosed
US-11857683-B2 Stabilization of phenobarbital sodium for injection SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) 2024-01-02 — — US disclosed
US-11857683-B2 Stabilization of phenobarbital sodium for injection SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) 2024-01-02 — — US disclosed
WO-2023175542-A1 STABILIZATION OF PHENOBARBITAL SODIUM FOR INJECTION SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) 2023-09-21 — — WO disclosed
US-11406598-B2 Lyophilized compositions of phenobarbital sodium salt Nivagen Pharmaceuticals, Inc. (US) 2022-08-09 — — US disclosed
US-11406598-B2 Lyophilized compositions of phenobarbital sodium salt Nivagen Pharmaceuticals, Inc. (US) 2022-08-09 — — US disclosed
US-20210085608-A1 Lyophilized Compositions of Phenobarbital Sodium Salt Nivagen Pharmaceuticals, Inc. (US) 2021-03-25 — — US disclosed
US-20210085608-A1 Lyophilized Compositions of Phenobarbital Sodium Salt Nivagen Pharmaceuticals, Inc. (US) 2021-03-25 — — US disclosed
US-9901576-B2 Stable formulation of phenobarbital sodium injection WEST-WARD PHARMACEUTICALS INTERNATIONAL LIMITED (GB) 2018-02-27 — — US disclosed
US-20170143719-A1 STABLE FORMULATION OF PHENOBARBITAL SODIUM INJECTION HIKMA PHARMACEUTICALS USA INC. 2017-05-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240082161-A1 STABILIZATION OF PHENOBARBITAL SODIUM FOR INJECTION PYGB, EPM2A, CACNA1A ALDH1A1 388/4885POLB 1005/4885KCNQ2 111/4885
US-20170143719-A1 STABLE FORMULATION OF PHENOBARBITAL SODIUM INJECTION F12, CPS1, PLPBP ALDH1A1 572/4885POLB 378/4885KCNQ2 3339/4885
US-20230031957-A1 STABILIZATION OF PHENOBARBITAL SODIUM FOR INJECTION EPM2A, PYGB, ATP6V1B2 ALDH1A1 256/4885POLB 1254/4885KCNQ2 147/4885
US-11857683-B2 Stabilization of phenobarbital sodium for injection EPM2A, PYGB, ATP6V1B2 ALDH1A1 256/4885POLB 1254/4885KCNQ2 147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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