Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 5/20 | 0.44 |
| ▸ | ATXN2 | Q99700 | 4/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 11/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL351769 | 0.88 | PTGDR2 (0.46) | ENPP2ATXN2PTGDR2TRPV1 | |
| SCHEMBL542701 | 0.78 | S1PR1 (0.41) | ENPP2ATXN2PTGDR2DGAT2 | |
| SCHEMBL542959 | 0.78 | HPGD (0.43) | ENPP2ATXN2PTGDR2 | |
| SCHEMBL351757 | 0.74 | PDE5A (0.38) | ENPP2ATXN2PTGDR2PDE5ATRPV1 | |
| SCHEMBL17112967 | 0.72 | ENPP2 (0.37) | ENPP2ATXN2PTGDR2PDE5ATRPV1 | |
| SCHEMBL17112952 | 0.72 | ENPP2 (0.36) | ENPP2ATXN2PTGDR2PDE5ATRPV1 | |
| SCHEMBL17112937 | 0.72 | ENPP2 (0.36) | ENPP2ATXN2PTGDR2PDE5ATRPV1 | |
| SCHEMBL543666 | 0.70 | KDM4A (0.44) | ENPP2ATXN2PTGDR2DGAT2 | |
| SCHEMBL11900910 | 0.67 | FNTA (0.37) | ENPP2ATXN2PTGDR2PDE5ADGAT2 | |
| SCHEMBL11900908 | 0.67 | FNTA (0.37) | ENPP2ATXN2PTGDR2PDE5ADGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120015976-A1 | AUTOTAXIN INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANK TER HAFTUNG (DE) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015976-A1 | AUTOTAXIN INHIBITORS | ENPP2, PLA2G12A, LPCAT1 | ENPP2 1/4885ATXN2 601/4885PTGDR2 1463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.