Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.42 |
| ▸ | AHR | P35869 | 2/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22612419 | 1.00 | HTR1A (0.46) | HTR1AHTR7ALDH1A1LMNAHTT | |
| SCHEMBL8420289 | 1.00 | HTR1A (0.46) | HTR1AHTR7ALDH1A1LMNAHTT | |
| SCHEMBL6926529 | 0.81 | HTR1A (0.45) | HTR1AHTR7ALDH1A1LMNAHTT | |
| Phenylethanolamine SCHEMBL21723498 | 0.81 | BLM (0.57) | HTR1AHTR7LMNASLC6A2SLC6A4 | |
| Phenylethanolamine SCHEMBL7150657 | 0.81 | BLM (0.57) | HTR1AHTR7LMNASLC6A2SLC6A4 | |
| SCHEMBL9338129 | 0.81 | LMNA (0.48) | HTR1AHTR7ALDH1A1LMNAHTT | |
| SCHEMBL14047172 | 0.81 | LMNA (0.48) | HTR1AHTR7ALDH1A1LMNAHTT | |
| Phenylethanolamine SCHEMBL296410 | 0.81 | BLM (0.57) | HTR1AHTR7LMNASLC6A2SLC6A4 | |
| SCHEMBL13778643 | 0.81 | LMNA (0.48) | HTR1AHTR7ALDH1A1LMNAHTT | |
| SCHEMBL27529169 | 0.81 | HTR1A (0.45) | HTR1AHTR7ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267100-A1 | Enzymatic synthesis of optically pure beta-hydroxy carboxylic acids and their derivatives | SOUTHERN METHODIST UNIVERSITY | 2010-10-21 | — | — | US | disclosed |