Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 5/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | APEX1 | P27695 | 3/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | RECQL | P46063 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.57 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylethanolamine SCHEMBL7150657 | 1.00 | BLM (0.57) | BLMTDP1KDM4EAPEX1TAAR1 | |
| Phenylethanolamine SCHEMBL21723498 | 1.00 | BLM (0.57) | BLMTDP1KDM4EAPEX1TAAR1 | |
| Phenylethanolamine SCHEMBL25831761 | 1.00 | BLM (0.57) | BLMTDP1KDM4EAPEX1TAAR1 | |
| Phenylethanolamine SCHEMBL5888034 | 0.98 | BLM (0.55) | BLMTDP1KDM4EAPEX1TAAR1 | |
| SCHEMBL7150293 | 0.82 | CYP3A4 (0.52) | BLMTDP1KDM4EAPEX1TAAR1 | |
| SCHEMBL3389189 | 0.82 | BLM (0.52) | BLMTDP1KDM4EAPEX1TAAR1 | |
| SCHEMBL8402037 | 0.82 | BLM (0.52) | BLMTDP1KDM4EAPEX1TAAR1 | |
| SCHEMBL11516250 | 0.82 | LMNA (0.42) | BLMTDP1KDM4EAPEX1TAAR1 | |
| Hydrochloric Acid SCHEMBL15511842 | 0.81 | BLM (0.50) | BLMTDP1KDM4EAPEX1TAAR1 | |
| Hydrochloric Acid SCHEMBL15517746 | 0.81 | BLM (0.50) | BLMTDP1KDM4EAPEX1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260042758-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | AGV DISCOVERY (FR) | 2026-02-12 | — | — | US | disclosed |
| US-12534439-B2 | Xanthohumol derivatives and methods for making and using | OREGON STATE UNIVERSITY (US) | 2026-01-27 | — | — | US | disclosed |
| US-12371429-B2 | Antibiotic resistance-modifying tricyclic heteroaryl compounds and uses thereof | RECREO PHARMACEUTICALS LLC (US) | 2025-07-29 | — | — | US | disclosed |
| US-20250138016-A1 | METHODS FOR THE DETECTION AND TREATMENT OF OVARIAN CANCER | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2025-05-01 | — | — | US | disclosed |
| US-20250060343-A1 | METHODS AND COMPOSITIONS FOR ANALYTE QUANTIFICATION | MATTERWORKS INC | 2025-02-20 | — | — | US | disclosed |
| US-12146869-B2 | Methods and compositions for analyte quantification | MATTERWORKS INC (US) | 2024-11-19 | — | — | US | disclosed |
| EP-4437319-A1 | METHODS AND COMPOSITIONS FOR ANALYTE QUANTIFICATION | Matterworks Inc (US) | 2024-10-02 | — | — | EP | disclosed |
| US-12100484-B2 | Methods and compositions for analyte quantification | MATTERWORKS INC (MA) | 2024-09-24 | — | — | US | disclosed |
| US-20240308997-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | AGV DISCOVERY (FR) | 2024-09-19 | — | — | US | disclosed |
| US-20240270705-A1 | COMPOUNDS SELECTIVE FOR JAK1 AND METHODS OF USE | VIVIDION THERAPEUTICS, INC. | 2024-08-15 | — | — | US | disclosed |
| EP-0294995-B1 | OXAZOLIDIN-2-ONE DERIVATIVES AS HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1992-11-11 | — | — | EP | disclosed |
| US-5153210-A | Hypoglycemic agent, animal growth regulator; veterinary medicine | BEECHAM GROUP P.L.C. (GB) | 1992-10-06 | — | — | US | disclosed |
| US-4968707-A | ANTIDIABETIC AGENTS | PFIZER INC. (US) | 1990-11-06 | — | — | US | disclosed |
| WO-1988009661-A1 | OXAZOLIDIN-2-ONE DERIVATIVES AS HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1988-12-15 | — | — | WO | disclosed |
| EP-0294995-A1 | Oxazolidin-2-one derivatives as hypoglycemic agents | PFIZER INC. (US) | 1988-12-14 | — | — | EP | disclosed |
| EP-0236624-A2 | Substituted phenyl ethanol amines, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1987-09-16 | — | — | EP | disclosed |
| EP-0171702-A1 | Benzoxazinone derivatives, preparation and use | BEECHAM GROUP PLC (GB) | 1986-02-19 | — | — | EP | disclosed |
| US-3983133-A | CNS ANTIDEPRESSANTS | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-09-28 | — | — | US | disclosed |
| US-3963718-A | CENTRAL NERVOUS SYSTEM ANTIDEPRESSANTS | JANSSEN PHARMACEUTICA (BE) | 1976-06-15 | — | — | US | disclosed |
| US-3947456-A | ANTIDEPRESSANTS | HOFFMAN-LA ROCHE INC. (US) | 1976-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12371429-B2 | Antibiotic resistance-modifying tricyclic heteroaryl compounds and uses thereof | CBR3, CBR1, CYP2B6 | BLM 1724/4885TDP1 3375/4885KDM4E 3576/4885 |
| US-12534439-B2 | Xanthohumol derivatives and methods for making and using | MT-CO1, MT-CO2, PC | BLM 4590/4885TDP1 1995/4885KDM4E 1260/4885 |
| US-20260042758-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | BRAF, RAF1, NRAS | BLM 4576/4885TDP1 2497/4885KDM4E 2556/4885 |
| US-20240270705-A1 | COMPOUNDS SELECTIVE FOR JAK1 AND METHODS OF USE | JAK2, JAK1, JAK3 | BLM 3673/4885TDP1 1777/4885KDM4E 1653/4885 |
| US-20240308997-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | MAPKAPK2, MAPK1, MAPK7 | BLM 4675/4885TDP1 2442/4885KDM4E 1485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.