SCHEMBL351100

SCHEMBL351100

O=COCc1cccc(C(F)(F)F)c1

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.62
PRKCA P17252 1/20 0.55
PRKCD Q05655 1/20 0.55
MAPT P10636 2/20 0.55
POLB P06746 1/20 0.55
MAOB P27338 8/20 0.53
NR4A2 P43354 2/20 0.51
ACP3 P15309 1/20 0.50
TAAR1 Q96RJ0 1/20 0.50
MMP1 P03956 1/20 0.48
MMP12 P39900 1/20 0.48
FFAR1 O14842 1/20 0.48
FFAR4 Q5NUL3 1/20 0.48
HTR2A P28223 1/20 0.47
HTR2C P28335 1/20 0.47
HTR2B P41595 1/20 0.47
MAOA P21397 1/20 0.47
HTT P42858 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5541823 0.87 IDO1 (0.46) IDO1PRKCAPRKCDMAPTPOLB
SCHEMBL2093850 0.83 TAAR1 (0.56) IDO1PRKCAPRKCDMAPTPOLB
SCHEMBL145681 0.82 IDO1 (0.57) IDO1
SCHEMBL11394076 0.81 MAOB (0.39) IDO1MAOBMAOA
SCHEMBL2095502 0.81 TAAR1 (0.53) IDO1PRKCAPRKCDMAPTPOLB
SCHEMBL2096391 0.80 TAAR1 (0.51) IDO1PRKCAPRKCDMAPTPOLB
SCHEMBL27708411 0.80 IDO1 (0.72) IDO1PRKCAPRKCDMAPTPOLB
SCHEMBL5540256 0.79 HDAC1 (0.50) IDO1PRKCAPRKCDMAPTPOLB
SCHEMBL28267284 0.78 IDO1 (0.70) IDO1PRKCAPRKCDMAPTPOLB
SCHEMBL39835 0.78 TAAR1 (0.56) IDO1MAPTPOLBMAOBACP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103270435-B Photosensitive transparent composition, color filter and method for producing the same, and solid-state imaging device 富士胶片株式会社 2017-10-24 CN disclosed
CN-103339537-B Light-shielding composition, method for producing same, solder resist, and method for forming pattern FUJIFILM CORP. (JP) 2016-02-03 CN disclosed
CN-102893215-B Polymerizable composition FUJIFILM CORP. (JP) 2015-10-21 CN disclosed
CN-103339537-A Light-shielding composition, method for producing light-shielding composition, solder resist, method for forming pattern, and solid-state imaging element FUJI PHOTO FILM CO LTD 2013-10-02 CN disclosed
CN-103270435-A Photosensitive transparent composition for color filter of solid-state imaging element, method for producing color filter of solid-state imaging element using same, color filter of solid-state imaging element, and solid-state imaging element FUJI PHOTO FILM CO LTD 2013-08-28 CN disclosed
US-8497283-B2 Autotaxin inhibitors MERCK PATENT GMBH (DE) 2013-07-30 US disclosed
CN-103038706-A Polymerizable composition FUJIFILM CORP 2013-04-10 CN disclosed
EP-2570418-A2 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2013-03-20 EP disclosed
US-20130023556-A1 AUTOTAXIN INHIBITORS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-01-24 US disclosed
CN-102893215-A Polymerizable composition FUJIFILM CORP 2013-01-23 CN disclosed
EP-1043310-B1 BIPHENYLAMIDINE DERIVATIVES TEIJIN LTD (JP) 2004-06-09 EP disclosed
US-6706745-B1 THERAPY FOR ANTICOAGULATION PLAYS AN IMPORTANT PART IN THE MEDICAL TREATMENT AND PROPHYLAXIS OF THROMBOEMBOLISMS TEIJIN LIMITED (JP) 2004-03-16 US disclosed
US-6676968-B1 AROMATIC AMIDINE DERIVATIVES COATED WITH PH DEPENDENT SOLUBLE ENTERIC POLYMER; IMPROVING ABSORPTION THROUGH DIGESTIVE TRACTS BY REDUCING CONTACT OF BILE OR PANCREATIC JUICE TEIJIN LIMITED (JP) 2004-01-13 US disclosed
US-20030203935-A1 Cyanobiphenyl derivatives TEIJIN LIMITED 2003-10-30 US disclosed
US-6538137-B1 Blood-coagulation factor X inhibitors TEIJIN LIMITED (JP) 2003-03-25 US disclosed
US-6348478-B1 BLOOD COAGULATION FACTORS AND ANTICOAGULANTS TEIJIN LIMITED (JP) 2002-02-19 US disclosed
EP-1179344-A1 RELEASE-REGULATING PREPARATIONS TEIJIN LIMITED (JP) 2002-02-13 EP disclosed
EP-1179527-A1 CYANOBIPHENYL DERIVATIVES TEIJIN LIMITED (JP) 2002-02-13 EP disclosed
EP-1043311-A1 BIPHENYLAMIDINE DERIVATIVES TEIJIN LIMITED (JP) 2000-10-11 EP disclosed
EP-1043310-A1 BIPHENYLAMIDINE DERIVATIVES TEIJIN LIMITED (JP) 2000-10-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130023556-A1 AUTOTAXIN INHIBITORS ENPP2, PLA2G12A, LPCAT1 IDO1 813/4885PRKCA 2052/4885PRKCD 3070/4885
US-20030203935-A1 Cyanobiphenyl derivatives F9, F12, F11 IDO1 1853/4885PRKCA 3767/4885PRKCD 3815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.