SCHEMBL3511025

SCHEMBL3511025

CC(N)(CO)CCc1ccc(C(=O)CCCCc2ccccc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.58
NPC1 O15118 2/20 0.54
RAB9A P51151 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
CASP3 P42574 1/20 0.54
SENP8 Q96LD8 1/20 0.54
SENP7 Q9BQF6 1/20 0.54
SENP6 Q9GZR1 1/20 0.54
THRA P10827 2/20 0.47
THRB P10828 2/20 0.47
TNNC1 P63316 5/20 0.45
S1PR1 P21453 3/20 0.45
S1PR3 Q99500 2/20 0.45
SGPL1 O95470 1/20 0.45
S1PR4 O95977 1/20 0.45
GPR183 P32249 1/20 0.45
CERS2 Q96G23 1/20 0.45
S1PR5 Q9H228 1/20 0.45
MAPT P10636 2/20 0.44
RXFP1 Q9HBX9 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3509404 1.00 DPP4 (0.58) DPP4NPC1RAB9ATDP1CASP3
SCHEMBL14168977 0.90 RAB9A (0.51) DPP4NPC1RAB9ATDP1CASP3
SCHEMBL295667 0.88 DPP4 (0.62) DPP4NPC1RAB9ATDP1CASP3
SCHEMBL27462751 0.88 DPP4 (0.62) DPP4NPC1RAB9ATDP1CASP3
SCHEMBL27529280 0.87 DPP4 (0.61) DPP4NPC1RAB9ATDP1CASP3
SCHEMBL3511410 0.87 DPP4 (0.61) DPP4NPC1RAB9ATDP1CASP3
Hydrochloric Acid SCHEMBL1820938 0.87 DPP4 (0.61) DPP4NPC1RAB9ATDP1CASP3
SCHEMBL5991627 0.87 DPP4 (0.61) DPP4NPC1RAB9ATDP1CASP3
SCHEMBL27553090 0.87 DPP4 (0.61) DPP4NPC1RAB9ATDP1CASP3
SCHEMBL7621778 0.86 TNNC1 (0.56) THRATHRBTNNC1S1PR1S1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080153882-A1 Pharmaceutical Composition Comprising Ppar Regulator DAIICHI SANKYO COMPANY, LIMITED (JP) 2008-06-26 US claimed
EP-1915994-A1 CYCLIC AMINE DERIVATIVE CONTAINING PPAR REGULATOR Sankyo Company, Limited (JP) 2008-04-30 EP claimed
US-20070149597-A1 Medicinal composition as immunosuppressant SANKYO COMPANY, LIMITED (JP) 2007-06-28 US claimed
EP-1782804-A1 MEDICINAL COMPOSITION AS IMMUNOSUPPRESSANT Sankyo Company, Limited (JP) 2007-05-09 EP claimed
EP-2045325-B1 DRUG-PHOSPHORYLATING ENZYME DAIICHI SANKYO CO LTD (JP) 2012-09-19 EP disclosed
EP-2045325-B1 DRUG-PHOSPHORYLATING ENZYME DAIICHI SANKYO CO LTD (JP) 2012-09-19 EP disclosed
US-20100248227-A1 DRUG-PHOSPHORYLATING ENZYME DAIICHI SANKYO COMPANY, LIMITED (JP) 2010-09-30 US disclosed
US-20100248227-A1 DRUG-PHOSPHORYLATING ENZYME DAIICHI SANKYO COMPANY, LIMITED (JP) 2010-09-30 US disclosed
US-20100248227-A1 DRUG-PHOSPHORYLATING ENZYME DAIICHI SANKYO COMPANY, LIMITED (JP) 2010-09-30 US disclosed
EP-2045325-A1 DRUG-PHOSPHORYLATING ENZYME Daiichi Sankyo Company, Limited (JP) 2009-04-08 EP disclosed
EP-2045325-A1 DRUG-PHOSPHORYLATING ENZYME Daiichi Sankyo Company, Limited (JP) 2009-04-08 EP disclosed
US-20080153882-A1 Pharmaceutical Composition Comprising Ppar Regulator DAIICHI SANKYO COMPANY, LIMITED (JP) 2008-06-26 US disclosed
EP-1915994-A1 CYCLIC AMINE DERIVATIVE CONTAINING PPAR REGULATOR Sankyo Company, Limited (JP) 2008-04-30 EP disclosed
US-20070149597-A1 Medicinal composition as immunosuppressant SANKYO COMPANY, LIMITED (JP) 2007-06-28 US disclosed
EP-1782804-A1 MEDICINAL COMPOSITION AS IMMUNOSUPPRESSANT Sankyo Company, Limited (JP) 2007-05-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080153882-A1 Pharmaceutical Composition Comprising Ppar Regulator PPARG, PPARA, PPARD DPP4 3499/4885NPC1 3921/4885RAB9A 3907/4885
US-20070149597-A1 Medicinal composition as immunosuppressant HMGCR, SHMT1, CYP11B1 DPP4 4767/4885NPC1 469/4885RAB9A 3164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.