SCHEMBL3511533

SCHEMBL3511533

O=C(O)Cc1cccc(Oc2cccc(OCc3ccccc3)c2)c1

nearest known ligand 0.77

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 5/20 0.59
FFAR4 Q5NUL3 1/20 0.59
NR4A2 P43354 1/20 0.59
LTB4R Q15722 1/20 0.56
LTB4R2 Q9NPC1 1/20 0.56
CYP4F2 P78329 1/20 0.56
CYP4A11 Q02928 1/20 0.56
MAOB P27338 2/20 0.56
KMT2A Q03164 2/20 0.54
MEN1 O00255 1/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
TSHR P16473 1/20 0.54
SMPD1 P17405 1/20 0.54
NAAA Q02083 1/20 0.53
BCHE P06276 1/20 0.53
KDM4E B2RXH2 1/20 0.52
ALDH1A1 P00352 1/20 0.52
PKM P14618 1/20 0.52
SRD5A2 P31213 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL954459 0.94 NR4A2 (0.66) FFAR1NR4A2LTB4RLTB4R2CYP4F2
SCHEMBL415441 0.87 FFAR1 (0.68) FFAR1FFAR4SRD5A2
Hydrochloric Acid SCHEMBL8694026 0.85 FFAR1 (0.67) FFAR1FFAR4SRD5A2
SCHEMBL2957881 0.85 MEN1 (0.67) FFAR1FFAR4NR4A2LTB4RLTB4R2
SCHEMBL6239573 0.85 FFAR1 (0.76) FFAR1FFAR4SRD5A2
SCHEMBL3508560 0.85 FFAR1 (0.59) FFAR1FFAR4LTB4RLTB4R2CYP4F2
SCHEMBL28237963 0.85 MAOB (0.72) NR4A2CYP4F2CYP4A11MAOBKMT2A
SCHEMBL3908596 0.85 CFD (0.66) FFAR1FFAR4NR4A2LTB4RLTB4R2
SCHEMBL3509948 0.84 PLA2G4B (0.54) FFAR1FFAR4CYP4F2CYP4A11SMN1; SMN2
Methane SCHEMBL27637860 0.84 FFAR1 (0.65) FFAR1FFAR4SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100267778-A1 Diphenyl ether compound, process for producing the same, and use ONO PHARMACEUTICAL CO., LTD. (JP) 2010-10-21 US disclosed
EP-1661879-A1 DIPHENYL ETHER COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE ONO PHARMACEUTICAL CO., LTD. (JP) 2006-05-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100267778-A1 Diphenyl ether compound, process for producing the same, and use PPARG, PPARD, PPARA FFAR1 6/4885FFAR4 7/4885NR4A2 105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.