Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 15/20 | 0.76 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.76 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.60 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6341082 | 0.90 | FFAR1 (0.68) | FFAR1FFAR4SRD5A2NR3C1AKR1B1 | |
| SCHEMBL14539208 | 0.88 | PTPRC (0.64) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL1745006 | 0.87 | FFAR1 (0.73) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL1745467 | 0.86 | FFAR1 (1.00) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL4760103 | 0.86 | MAOB (0.67) | FFAR1FFAR4 | |
| SCHEMBL6337243 | 0.86 | ALOX5 (0.59) | FFAR1FFAR4SRD5A2NR3C1 | |
| SCHEMBL3511533 | 0.85 | FFAR1 (0.59) | FFAR1FFAR4SRD5A2 | |
| SCHEMBL8969156 | 0.85 | SRD5A2 (0.70) | FFAR1FFAR4SRD5A2NR3C1AKR1B1 | |
| SCHEMBL415441 | 0.85 | FFAR1 (0.68) | FFAR1FFAR4SRD5A2NR3C1AKR1B1 | |
| SCHEMBL1066614 | 0.85 | FFAR1 (0.70) | FFAR1FFAR4SRD5A2AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | claimed |
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | disclosed |