Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1827268 | 0.85 | CA1 (0.40) | L3MBTL1CA1CA2ACHELPAR1 | |
| SCHEMBL1827115 | 0.85 | ACHE (0.40) | L3MBTL1CA1CA2ACHELPAR1 | |
| SCHEMBL1823696 | 0.83 | CA1 (0.42) | L3MBTL1CA1CA2ACHELPAR1 | |
| SCHEMBL4880333 | 0.82 | CA2 (0.49) | L3MBTL1CA1CA2ACHEGABRA1 | |
| SCHEMBL27905121 | 0.82 | SLC22A6 (0.42) | L3MBTL1CA1CA2ACHELPAR1 | |
| SCHEMBL1822664 | 0.82 | CA1 (0.38) | L3MBTL1CA1CA2ACHE | |
| SCHEMBL1826155 | 0.82 | TYR (0.41) | L3MBTL1CA1CA2ACHEPOLB | |
| SCHEMBL1827334 | 0.82 | TSHR (0.47) | L3MBTL1CA1CA2ACHE | |
| SCHEMBL1826953 | 0.80 | CA1 (0.37) | L3MBTL1CA1CA2ACHE | |
| SCHEMBL2839036 | 0.80 | MMP2 (0.47) | CA1CA2ACHEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102786486-A | Preparation method of thiophenol antioxidant | TAIZHOU VOCATIONAL & TECHNICAL COLLEGE | 2012-11-21 | — | — | CN | disclosed |
| US-20100286145-A1 | ISOPHTHALAMIDE DERIVATIVES INHIBITING BETA-SECRETASE ACTIVITY | COMENTIS, INC. (US) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286145-A1 | ISOPHTHALAMIDE DERIVATIVES INHIBITING BETA-SECRETASE ACTIVITY | BACE1, BACE2, APP | L3MBTL1 815/4885CA1 733/4885CA2 3501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.