Phytonadione

Phytonadione

SCHEMBL351365

CC(=CCC1=C(C)C(=O)c2ccccc2C1=O)CCC[C@H](C)CCC[C@H](C)CCCC(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 2/20 1.00
PDE4A P27815 2/20 1.00
SNCA P37840 2/20 1.00
PDE3A Q14432 2/20 1.00
PGR P06401 1/20 0.61
HTR1A P08908 1/20 0.61
ADORA3 P0DMS8 1/20 0.61
MAPT P10636 1/20 0.61
MAPK1 P28482 1/20 0.61
DRD3 P35462 1/20 0.61
PTPN1 P18031 4/20 0.48
PTPN2 P17706 2/20 0.45
CDC25B P30305 2/20 0.45
DHODH Q02127 1/20 0.40
MAOB P27338 2/20 0.40
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phytonadione SCHEMBL419597 1.00 PTGS1 (1.00) PTGS1PDE4ASNCAPDE3APGR
SCHEMBL9956594 1.00 PTGS1 (1.00) PTGS1PDE4ASNCAPDE3APGR
Phytonadione SCHEMBL29845402 1.00 PTGS1 (1.00) PTGS1PDE4ASNCAPDE3APGR
SCHEMBL14379723 1.00 PTGS1 (1.00) PTGS1PDE4ASNCAPDE3APGR
Phytonadione SCHEMBL3882 1.00 PTGS1 (1.00) PTGS1PDE4ASNCAPDE3APGR
Phytonadione SCHEMBL351364 1.00 PTGS1 (1.00) PTGS1PDE4ASNCAPDE3APGR
Phytonadione SCHEMBL8710454 1.00 PTGS1 (1.00) PTGS1PDE4ASNCAPDE3APGR
Phytonadione SCHEMBL8756574 1.00 PTGS1 (1.00) PTGS1PDE4ASNCAPDE3APGR
Phytonadione SCHEMBL30144830 1.00 PTGS1 (1.00) PTGS1PDE4ASNCAPDE3APGR
Phytonadione SCHEMBL28180925 0.99 PTGS1 (0.98) PTGS1PDE4ASNCAPDE3APGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108482755-B Food package sealing machine 徐州工程学院 2020-08-25 CN claimed
WO-2016038626-A1 PHARMACEUTICAL COMPOSITIONS OF VITAMIN KL EMCURE PHARMACEUTICALS LIMITED (IN) 2016-03-17 WO claimed
US-20150283290-A1 STERILIZED COMPOSITIONS OF CYANOACRYLATE MONOMERS AND NAPHTHOQUINONE 2,3-OXIDES ADHEZION BIOMEDICAL, LLC (US) 2015-10-08 US claimed
US-20040122123-A1 Pultrusion apparatus for continuous fabrication of fiber-reinforced plastic articles having a non-linear shape, methods of fabricating such articles, and compositions used therein KUSY ROBERT P 2004-06-24 US claimed
US-20020180112-A1 Pultrusion apparatus for continuous fabrication of fiber-reinforced plastic articles having a non-linear shape, methods of fabricating such articles and compositions used therein UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, THE 2002-12-05 US claimed
US-12295957-B2 Ascorbic acid and quinone compounds in combination with an antiparasitic agent for treating a parasitic disease IC-MedTech Corp. (US) 2025-05-13 US disclosed
US-20240398755-A1 ASCORBIC ACID AND QUINONE COMPOUNDS FOR TREATING CHAGAS DISEASE IC-MedTech Corp. 2024-12-05 US disclosed
US-12070439-B2 Phytonadione compositions and related methods EXELA HOLDINGS, INC. (US) 2024-08-27 US disclosed
CN-117517549-B Method for simultaneously detecting VK1, MK-4 and MK-7 in milk and application of extractant and reagent combination 湖南凯莱谱生物科技有限公司 2024-06-11 CN disclosed
US-11998523-B2 Ascorbic acid and quinone compounds for treating Chagas disease IC-MedTech Corp. (US) 2024-06-04 US disclosed
US-20240165084-A1 ASCORBIC ACID AND QUINONE COMPOUNDS IN COMBINATION WITH AN ANTIPARASITIC AGENT FOR TREATING A PARASITIC DISEASE IC-MedTech Corp. 2024-05-23 US disclosed
CN-117849233-A Method for detecting phylloquinone drop related substances 北京阳光诺和药物研究股份有限公司 2024-04-09 CN disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
US-4734282-A Rodenticidal compositions containing 1,4-naphthoquinone derivatives DUKE UNIVERSITY (US) 1988-03-29 US disclosed
EP-0244309-A2 Rodenticidal compositions containing 1,4-naphthoquinone derivatives DUKE UNIVERSITY (US) 1987-11-04 EP disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed
EP-0155812-A2 Dental compositions KURARAY CO., LTD. (JP) 1985-09-25 EP disclosed
US-4525350-A Methods of stimulating host defense system with coenzymes Q4 to Q.sub.1 THE NEW ENGLAND INSTITUTE, INC. (US) 1985-06-25 US disclosed
EP-0117321-A2 Foodstuffs, including chewing gum with anti-caries activity, and processes for preparing them TABAGH AG (CH) 1984-09-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12070439-B2 Phytonadione compositions and related methods UGT2B17, UGT1A10, CYP17A1 PTGS1 1110/4885PDE4A 1983/4885SNCA 2155/4885
US-20240165084-A1 ASCORBIC ACID AND QUINONE COMPOUNDS IN COMBINATION WITH AN ANTIPARASITIC AGENT FOR TREATING A PARASITIC DISEASE NQO1, ADH7, CYP27B1 PTGS1 2170/4885PDE4A 2540/4885SNCA 587/4885
US-11998523-B2 Ascorbic acid and quinone compounds for treating Chagas disease NQO1, ADH7, TALDO1 PTGS1 2195/4885PDE4A 2261/4885SNCA 715/4885
US-12295957-B2 Ascorbic acid and quinone compounds in combination with an antiparasitic agent for treating a parasitic disease NQO1, ADH7, CYP27B1 PTGS1 2170/4885PDE4A 2540/4885SNCA 587/4885
US-20240398755-A1 ASCORBIC ACID AND QUINONE COMPOUNDS FOR TREATING CHAGAS DISEASE NQO1, ADH7, TALDO1 PTGS1 2195/4885PDE4A 2261/4885SNCA 715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.