Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 1.00 |
| ▸ | PDE4A | P27815 | 2/20 | 1.00 |
| ▸ | SNCA | P37840 | 2/20 | 1.00 |
| ▸ | PDE3A | Q14432 | 2/20 | 1.00 |
| ▸ | PGR | P06401 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.45 |
| ▸ | CDC25B | P30305 | 2/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phytonadione SCHEMBL419597 | 1.00 | PTGS1 (1.00) | PTGS1PDE4ASNCAPDE3APGR | |
| SCHEMBL9956594 | 1.00 | PTGS1 (1.00) | PTGS1PDE4ASNCAPDE3APGR | |
| Phytonadione SCHEMBL351365 | 1.00 | PTGS1 (1.00) | PTGS1PDE4ASNCAPDE3APGR | |
| Phytonadione SCHEMBL29845402 | 1.00 | PTGS1 (1.00) | PTGS1PDE4ASNCAPDE3APGR | |
| SCHEMBL14379723 | 1.00 | PTGS1 (1.00) | PTGS1PDE4ASNCAPDE3APGR | |
| Phytonadione SCHEMBL3882 | 1.00 | PTGS1 (1.00) | PTGS1PDE4ASNCAPDE3APGR | |
| Phytonadione SCHEMBL351364 | 1.00 | PTGS1 (1.00) | PTGS1PDE4ASNCAPDE3APGR | |
| Phytonadione SCHEMBL8756574 | 1.00 | PTGS1 (1.00) | PTGS1PDE4ASNCAPDE3APGR | |
| Phytonadione SCHEMBL30144830 | 1.00 | PTGS1 (1.00) | PTGS1PDE4ASNCAPDE3APGR | |
| Phytonadione SCHEMBL28180925 | 0.99 | PTGS1 (0.98) | PTGS1PDE4ASNCAPDE3APGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0679394-B1 | Menatetronome derivative as antiarteriosclerotic agent | EISAI CO LTD (JP) | 1998-01-14 | — | — | EP | claimed |
| EP-0679394-A2 | Menatetronome derivative as antiarteriosclerotic agent | Eisai Co., Ltd. (JP) | 1995-11-02 | — | — | EP | claimed |
| US-11234975-B2 | Levorphanol prodrugs and processes for making and using them | KEMPHARM, INC. (US) | 2022-02-01 | — | — | US | disclosed |
| US-20210002226-A1 | LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM | ALTER DOMUS (US) LLC | 2021-01-07 | — | — | US | disclosed |
| US-20200390757-A1 | LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM | ALTER DOMUS (US) LLC | 2020-12-17 | — | — | US | disclosed |
| EP-0679394-B1 | Menatetronome derivative as antiarteriosclerotic agent | EISAI CO LTD (JP) | 1998-01-14 | — | — | EP | disclosed |
| EP-0679394-A2 | Menatetronome derivative as antiarteriosclerotic agent | Eisai Co., Ltd. (JP) | 1995-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200390757-A1 | LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM | OPRM1, OPRL1, OPRK1 | PTGS1 885/4885PDE4A 1641/4885SNCA 1727/4885 |
| US-11234975-B2 | Levorphanol prodrugs and processes for making and using them | OPRM1, OPRL1, OPRK1 | PTGS1 885/4885PDE4A 1641/4885SNCA 1727/4885 |
| US-20210002226-A1 | LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM | OPRM1, OPRK1, OPRD1 | PTGS1 677/4885PDE4A 1221/4885SNCA 1599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.