SCHEMBL3514520

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9726919	0.83	MAPT (0.58)	MAPTTDP1TUBB1PDE4DMEN1
	SCHEMBL3556531	0.82	NPC1 (0.53)	MAPTMEN1KMT2AALDH1A1NPC1
	SCHEMBL102827	0.82	MAPT (0.72)	MAPTTDP1TUBB1PDE4DMEN1
	SCHEMBL1421887	0.82	ALDH1A1 (0.59)	MAPTTDP1TUBB1PDE4DMEN1
	SCHEMBL4913002	0.82	MAPT (0.56)	MAPTTDP1TUBB1PDE4DMEN1
	SCHEMBL30069060	0.82	ALDH1A1 (0.59)	MAPTTDP1TUBB1PDE4DMEN1
	Methyl 2,3,4-Trimethoxybenzoate SCHEMBL1434191	0.80	ALDH1A1 (0.57)	MAPTTDP1TUBB1PDE4DMEN1
	Hydrochloric Acid SCHEMBL5061862	0.80	MAPT (0.70)	MAPTTDP1TUBB1PDE4DMEN1
	SCHEMBL8526786	0.80	MAPT (0.55)	MAPTTDP1TUBB1PDE4DMEN1
	SCHEMBL4638173	0.80	MAPT (0.55)	MAPTTDP1TUBB1PDE4DMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.