Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726919 | 0.85 | MAPT (0.58) | MAPTTDP1PDE4DALDH1A1MEN1 | |
| SCHEMBL102827 | 0.83 | MAPT (0.72) | MAPTTDP1PDE4DALDH1A1MEN1 | |
| SCHEMBL1421887 | 0.83 | ALDH1A1 (0.59) | MAPTTDP1PDE4DALDH1A1MEN1 | |
| SCHEMBL30069060 | 0.83 | ALDH1A1 (0.59) | MAPTTDP1PDE4DALDH1A1MEN1 | |
| SCHEMBL660605 | 0.82 | MAPT (0.55) | MAPTTDP1PDE4DALDH1A1MEN1 | |
| Water SCHEMBL9749470 | 0.82 | MAPT (0.70) | MAPTTDP1PDE4DALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL5061862 | 0.82 | MAPT (0.70) | MAPTTDP1PDE4DALDH1A1MEN1 | |
| Methyl 2,3,4-Trimethoxybenzoate SCHEMBL1434191 | 0.82 | ALDH1A1 (0.57) | MAPTTDP1PDE4DALDH1A1MEN1 | |
| SCHEMBL3514520 | 0.82 | MAPT (0.55) | MAPTTDP1PDE4DALDH1A1MEN1 | |
| SCHEMBL222062 | 0.82 | MAPT (0.55) | MAPTTDP1PDE4DALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450109-A | VASODILATION; CARDIOTONIC AGENTS; HYPOTENSIVE AGENTS | SS PHARMACEUTICAL CO., LTD. (JP) | 1984-05-22 | — | — | US | claimed |
| US-20080107829-A1 | Cellulose compound, cellulose film, optical compensation sheet, polarizing plate, and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2008-05-08 | — | — | US | disclosed |