Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipyridyl SCHEMBL3927610 | 0.86 | KDM4E (0.46) | ALDH1A1KDM4EPOLBCCR1CCR5 | |
| SCHEMBL14988156 | 0.76 | KDM1A (0.44) | ALDH1A1KDM4EPOLBCCR1CCR5 | |
| SCHEMBL25742607 | 0.75 | KEAP1 (0.47) | KEAP1CRHR1KMT2A | |
| SCHEMBL14988418 | 0.74 | KEAP1 (0.50) | ALDH1A1KDM4EPOLBADRA2AADRA2B | |
| SCHEMBL29374702 | 0.73 | CA12 (0.46) | ALDH1A1KDM4EPOLBADRA2AADRA2B | |
| SCHEMBL1069905 | 0.73 | CA12 (0.46) | ALDH1A1KDM4EPOLBADRA2AADRA2B | |
| SCHEMBL29758358 | 0.73 | CA12 (0.46) | ALDH1A1KDM4EPOLBADRA2AADRA2B | |
| SCHEMBL2406888 | 0.73 | PDK1 (0.46) | ALDH1A1KDM4EPOLBPDE10ACASP1 | |
| SCHEMBL16835813 | 0.73 | ALOX5AP (0.38) | ALDH1A1KDM4EPOLBPDE10AADRA2A | |
| SCHEMBL16685761 | 0.72 | FYN (0.42) | ALDH1A1MEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8951400-B2 | Chemistry used in biosensors | OHMX CORPORATION (US) | 2015-02-10 | — | — | US | disclosed |
| WO-2012012537-A1 | NOVEL CHEMISTRY USED IN BIOSENSORS | OHMX CORPORATION (US) | 2012-01-26 | — | — | WO | disclosed |
| US-20120012472-A1 | NOVEL CHEMISTRY USED IN BIOSENSORS | OHMX CORPORATION (US) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120012472-A1 | NOVEL CHEMISTRY USED IN BIOSENSORS | SSBP1, OSGEP, OCIAD2 | ALDH1A1 3098/4885KDM4E 4331/4885POLB 118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.