Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A2 | O43868 | 2/20 | 0.45 |
| ▸ | PI4KA | P42356 | 3/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.44 |
| ▸ | SLC28A1 | O00337 | 2/20 | 0.44 |
| ▸ | GAPDH | P04406 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | STAT6 | P42226 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.44 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9491636 | 0.88 | ADORA3 (0.47) | SLC28A2PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL1434028 | 0.85 | ADORA3 (0.49) | SLC28A2PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL10645028 | 0.84 | ADORA3 (0.42) | SLC28A2PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL9341012 | 0.84 | PI4KA (0.43) | SLC28A2PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL7208241 | 0.83 | ADORA3 (0.43) | SLC28A2PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL28905612 | 0.83 | ADORA3 (0.42) | SLC28A2PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL10345558 | 0.82 | ADORA3 (0.42) | SLC28A2PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL10606024 | 0.81 | SLC28A2 (0.49) | SLC28A2PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL6426189 | 0.81 | SLC28A2 (0.43) | SLC28A2PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL27412560 | 0.80 | ADORA3 (0.39) | SLC28A2PI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135092-A1 | INHIBITORS OF RecA ACTIVITIES FOR CONTROL OF ANTIBIOTIC-RESISTANT BACTERIAL PATHOGENS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, THE | 2012-05-31 | — | — | US | disclosed |
| US-20100292135-A1 | INHIBITORS OF RecA ACTIVITIES FOR CONTROL OF ANTIBIOTIC-RESISTANT BACTERIAL PATHOGENS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-11-18 | — | — | US | disclosed |
| US-20060199768-A1 | Inhibitors of RecA activities for control of antibiotic-resistant bacterial pathogens | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2006-09-07 | — | — | US | disclosed |
| EP-0179631-B1 | N6-ACENAPHTHYL ADENOSINES AND ANALOGS THEREOF | WARNER-LAMBERT COMPANY (US) | 1989-04-26 | — | — | EP | disclosed |
| EP-0179631-A2 | N6-acenaphthyl adenosines and analogs thereof | WARNER-LAMBERT COMPANY (US) | 1986-04-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199768-A1 | Inhibitors of RecA activities for control of antibiotic-resistant bacterial pathogens | RECQL, DNA2, WRN | SLC28A2 1836/4885PI4KA 3242/4885PI4K2B 3921/4885 |
| US-20100292135-A1 | INHIBITORS OF RecA ACTIVITIES FOR CONTROL OF ANTIBIOTIC-RESISTANT BACTERIAL PATHOGENS | RECQL, DNA2, WRN | SLC28A2 1836/4885PI4KA 3242/4885PI4K2B 3921/4885 |
| US-20120135092-A1 | INHIBITORS OF RecA ACTIVITIES FOR CONTROL OF ANTIBIOTIC-RESISTANT BACTERIAL PATHOGENS | RECQL, WRN, ADAR | SLC28A2 1227/4885PI4KA 3047/4885PI4K2B 3819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.