SCHEMBL6426189

SCHEMBL6426189

Nc1ncnc2c1ncn2[C@]1(C(=O)c2cccc3ccccc23)O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC28A2 O43868 2/20 0.43
NNMT P40261 4/20 0.42
PI4KA P42356 3/20 0.42
PI4K2B Q8TCG2 3/20 0.42
PI4K2A Q9BTU6 3/20 0.42
PI4KB Q9UBF8 3/20 0.42
ADORA3 P0DMS8 5/20 0.42
ADORA2A P29274 3/20 0.42
P2RX1 P51575 1/20 0.42
P2RX3 P56373 1/20 0.42
P2RX4 Q99571 1/20 0.42
P2RX7 Q99572 1/20 0.42
P2RX2 Q9UBL9 1/20 0.42
DOT1L Q8TEK3 2/20 0.42
DPP4 P27487 1/20 0.42
MEN1 O00255 1/20 0.42
SLC28A1 O00337 1/20 0.42
MAP3K7 O43318 1/20 0.42
GAPDH P04406 1/20 0.42
MAPK1 P28482 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31644935 0.86 EGFR (0.47) SLC28A2PI4KAPI4K2BPI4K2API4KB
SCHEMBL441536 0.86 EGFR (0.47) SLC28A2PI4KAPI4K2BPI4K2API4KB
SCHEMBL2292790 0.84 ADORA3 (0.41) SLC28A2PI4KAPI4K2BPI4K2API4KB
SCHEMBL30041710 0.83 DOT1L (0.45) SLC28A2PI4KAPI4K2BPI4K2API4KB
Phosphoric Acid SCHEMBL16070005 0.83 ADORA3 (0.42) SLC28A2PI4KAPI4K2BPI4K2API4KB
SCHEMBL9501856 0.82 EGFR (0.43) SLC28A2PI4KAPI4K2BPI4K2API4KB
SCHEMBL2463541 0.82 ADORA3 (0.50) SLC28A2PI4KAPI4K2BPI4K2API4KB
SCHEMBL29655156 0.82 ADORA3 (0.50) SLC28A2PI4KAPI4K2BPI4K2API4KB
SCHEMBL219553 0.81 ADORA3 (0.49) SLC28A2PI4KAPI4K2BPI4K2API4KB
SCHEMBL3514758 0.81 SLC28A2 (0.45) SLC28A2PI4KAPI4K2BPI4K2API4KB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0506830-B1 UNCHARGED MORPHOLINO-BASED POLYMERS HAVING PHOSPHOROUS-CONTAINING CHIRAL INTERSUBUNIT LINKAGES AVI BIOPHARMA INC (US) 2005-12-14 EP disclosed
EP-0962463-B1 Uncharged morpholino-based polymers having phosphorus-containing chiral intersubunit linkages ANTIVIRALS INC (US) 2002-07-10 EP disclosed
EP-0962463-A1 Uncharged morpholino-based polymers having phosphorus-containing chiral intersubunit linkages ANTIVIRALS INC. (US) 1999-12-08 EP disclosed
EP-0506845-B1 UNCHARGED MORPHOLINO-BASED POLYMERS HAVING ACHIRAL INTERSUBUNIT LINKAGES ANTIVIRALS INC (US) 1998-03-18 EP disclosed
US-5521063-A Polynucleotide reagent containing chiral subunits and methods of use ANTIVIRALS INC. (US) 1996-05-28 US disclosed
US-5378841-A Alpha-morpholino ribonucleoside derivatives and polymers thereof ANTIVIRALS INC. (US) 1995-01-03 US disclosed
US-5235033-A ALPHA-MORPHOLINO RIBONUCLEOSIDE DERIVATIVES AND POLYMERS THEREOF ANTI-GENE DEVELOPMENT GROUP (US) 1993-08-10 US disclosed
US-5185444-A Uncharged morpolino-based polymers having phosphorous containing chiral intersubunit linkages ANTI-GENE DEVEOPMENT GROUP (US) 1993-02-09 US disclosed
EP-0506830-A4 UNCHARGED MORPHOLINO-BASED POLYMERS HAVING PHOSPHOROUS-CONTAINING CHIRAL INTERSUBUNIT LINKAGES 1993-01-07 EP disclosed
EP-0506845-A4 UNCHARGED MORPHOLINO-BASED POLYMERS HAVING ACHIRAL INTERSUBUNIT LINKAGES 1992-10-21 EP disclosed
EP-0506845-A1 UNCHARGED MORPHOLINO-BASED POLYMERS HAVING ACHIRAL INTERSUBUNIT LINKAGES ANTIVIRALS INC. (US) 1992-10-07 EP disclosed
EP-0506830-A1 UNCHARGED MORPHOLINO-BASED POLYMERS HAVING PHOSPHOROUS-CONTAINING CHIRAL INTERSUBUNIT LINKAGES ANTIVIRALS INC. (US) 1992-10-07 EP disclosed
US-5034506-A Polymers for the determination of genetic sequences and viral diseases ANTI-GENE DEVELOPMENT GROUP (US) 1991-07-23 US disclosed
WO-1991009033-A1 UNCHARGED MORPHOLINO-BASED POLYMERS HAVING PHOSPHOROUS-CONTAINING CHIRAL INTERSUBUNIT LINKAGES ANTI-GENE DEVELOPMENT GROUP (US) 1991-06-27 WO disclosed
WO-1991009073-A1 UNCHARGED MORPHOLINO-BASED POLYMERS HAVING ACHIRAL INTERSUBUNIT LINKAGES ANTI-GENE DEVELOPMENT GROUP (US) 1991-06-27 WO disclosed