Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3515163 | 0.74 | KDM4E (0.36) | ALDH1A1THRATHRBTSHR | |
| SCHEMBL3515157 | 0.74 | KDM4E (0.36) | ALDH1A1THRATHRBTSHR | |
| SCHEMBL446035 | 0.74 | CYP4F2 (0.44) | CA2MAPK1ALDH1A1TP53TSHR | |
| SCHEMBL2690161 | 0.71 | CA2 (0.38) | CA2MAPK1ALDH1A1CA1TP53 | |
| SCHEMBL8960878 | 0.70 | ATM (0.37) | CA2MAPK1ALDH1A1TP53TSHR | |
| SCHEMBL11128347 | 0.70 | ALDH1A1 (0.41) | CA2MAPK1ALDH1A1CA1TSHR | |
| SCHEMBL3516780 | 0.69 | — | — | |
| SCHEMBL3516784 | 0.69 | — | — | |
| SCHEMBL11138013 | 0.69 | CA1 (0.45) | CA2MAPK1ALDH1A1CA1TSHR | |
| SCHEMBL11138012 | 0.69 | ALDH1A1 (0.40) | CA2MAPK1ALDH1A1CA1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236917-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20100240855-A1 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |