Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PLA2G2C | Q5R387 | 4/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3515163 | 1.00 | KDM4E (0.36) | KDM4EUSP2ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL446836 | 0.75 | ACE2 (0.46) | KDM4EUSP2ALDH1A1ALOX15PLA2G2C | |
| SCHEMBL3516780 | 0.75 | — | — | |
| SCHEMBL16299711 | 0.75 | ACE2 (0.46) | KDM4EUSP2ALDH1A1ALOX15PLA2G2C | |
| SCHEMBL3515161 | 0.74 | CA2 (0.33) | ALDH1A1TSHRTHRATHRB | |
| SCHEMBL3518740 | 0.70 | RNPEP (0.34) | ALDH1A1 | |
| SCHEMBL3518747 | 0.70 | RNPEP (0.34) | ALDH1A1 | |
| SCHEMBL11844397 | 0.70 | USP2 (0.48) | USP2PLA2G2CSPHK1CYP1A2CYP3A4 | |
| SCHEMBL445182 | 0.70 | ALDH1A1 (0.48) | USP2ALDH1A1SMN1; SMN2PLA2G2CSPHK1 | |
| SCHEMBL16299717 | 0.68 | HSD17B10 (0.49) | USP2ALDH1A1PLA2G2CSPHK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236917-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20100240855-A1 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |