SCHEMBL3516271

SCHEMBL3516271

O=C(O)C(C(=O)O)C1(C(C(=O)O)C(=O)O)CCC1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
NFKB1 P19838 1/20 0.37
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8639460 0.92 CYP2C19 (0.36) TSHRNFKB1CYP2C19
SCHEMBL27672185 0.88 FFAR3 (0.32) TSHRNFKB1CYP2C19
SCHEMBL6287567 0.75 ALDH1A1 (0.33) TSHRCYP2C19
SCHEMBL8670866 0.65 CYP2C19 (0.38) TSHRNFKB1CYP2C19
SCHEMBL8158504 0.65 MME (0.36) TSHRNFKB1CYP2C19
SCHEMBL14578713 0.64 GRM1 (0.40) TSHRNFKB1CYP2C19
SCHEMBL5295187 0.64 GRM1 (0.40) TSHRNFKB1CYP2C19
SCHEMBL25220493 0.61 TSHR (0.39) TSHRNFKB1CYP2C19
SCHEMBL28945972 0.60
SCHEMBL27979481 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9983196-B2 Compositions and methods for optimizing drug hydrophobicity and drug delivery to cells BIOELASTICS, INC. (US) 2018-05-29 US disclosed
US-20140186871-A1 COMPOSITIONS AND METHODS FOR OPTIMIZING DRUG HYDROPHOBICITY AND DRUG DELIVERY TO CELLS BIOELASTICS, INC. 2014-07-03 US disclosed
US-8626452-B2 Compositions and methods for optimizing drug hydrophobicity and drug delivery to cells BIOELASTICS, INC. 2014-01-07 US disclosed
US-20100330606-A1 COMPOSITIONS AND METHODS FOR OPTIMIZING DRUG HYDROPHOBICITY AND DRUG DELIVERY TO CELLS URRY INTELLECTUAL PROPERTY LLC (US) 2010-12-30 US disclosed
WO-2010144612-A1 COMPOSITIONS AND METHODS FOR OPTIMIZING DRUG HYDROPHOBICITY AND DRUG DELIVERY TO CELLS URRY INTELLECTUAL PROPERTY LLC (US) 2010-12-16 WO disclosed