Cyclophenazine

Cyclophenazine

SCHEMBL351628

FC(F)(F)c1ccc2c(c1)N(CCCN1CCN(C3CC3)CC1)c1ccccc1S2

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 12/20 0.77
LMNA P02545 6/20 0.77
MAPT P10636 6/20 0.77
SMN1; SMN2 Q16637 5/20 0.77
CYP3A4 P08684 4/20 0.77
MAPK1 P28482 4/20 0.77
TP53 P04637 3/20 0.77
RAD52 P43351 3/20 0.77
ALDH1A1 P00352 2/20 0.77
CYP1A2 P05177 2/20 0.77
ABCB1 P08183 2/20 0.77
HTR1A P08908 2/20 0.77
ADRA2A P08913 2/20 0.77
ADORA3 P0DMS8 2/20 0.77
CYP2D6 P10635 2/20 0.77
CHRM1 P11229 2/20 0.77
DRD2 P14416 2/20 0.77
ADRA2B P18089 2/20 0.77
ADRA2C P18825 2/20 0.77
NFKB1 P19838 2/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclophenazine SCHEMBL29710907 1.00 FPR2 (0.77) FPR2LMNAMAPTSMN1; SMN2CYP3A4
Cyclophenazine SCHEMBL28173472 0.99 LMNA (0.77) FPR2LMNAMAPTSMN1; SMN2CYP3A4
Cyclophenazine SCHEMBL122920 0.99 LMNA (0.77) FPR2LMNAMAPTSMN1; SMN2CYP3A4
SCHEMBL31673764 0.92 FPR2 (0.79) FPR2LMNAMAPTSMN1; SMN2CYP3A4
SCHEMBL20412084 0.92 FPR2 (0.79) FPR2LMNAMAPTSMN1; SMN2CYP3A4
SCHEMBL20412094 0.91 FPR2 (0.81) FPR2LMNAMAPTSMN1; SMN2CYP3A4
SCHEMBL30703686 0.91 FPR2 (0.81) FPR2LMNAMAPTSMN1; SMN2CYP3A4
SCHEMBL20412107 0.90 FPR2 (0.79) FPR2LMNAMAPTSMN1; SMN2CYP3A4
SCHEMBL31673755 0.90 FPR2 (0.79) FPR2LMNAMAPTSMN1; SMN2CYP3A4
SCHEMBL20427426 0.89 FPR2 (0.72) FPR2LMNAMAPTSMN1; SMN2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1931320-B1 MICROPARTICLES WITH MODIFIED RELEASE OF AT LEAST ONE ACTIVE PRINCIPLE AND ORAL DOSAGE FORM COMPRISING THE SAME FLAMEL IRELAND LTD (IE) 2022-06-15 EP claimed
CN-106456662-A Compositions of pentosan polysulfate for oral administration and methods of use thereof 奥利金制药公司 2017-02-22 CN claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
US-20090220611-A1 Microparticles With Modified Release of At Least One Active Principle and Oral Pharmaceutical Form Comprising Same FLAMEL TECHNOLOGIES, S.A. (FR) 2009-09-03 US claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
EP-1931320-A2 MICROPARTICLES WITH MODIFIED RELEASE OF AT LEAST ONE ACTIVE PRINCIPLE AND ORAL GALENIC FORM COMPRISING SAME Flamel Technologies (FR) 2008-06-18 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
WO-2007036671-A2 MICROPARTICLES WITH MODIFIED RELEASE OF AT LEAST ONE ACTIVE PRINCIPLE AND ORAL GALENIC FORM COMPRISING SAME FLAMEL TECHNOLOGIES (FR) 2007-04-05 WO claimed
EP-1044023-B1 A COVALENT CONJUGATE OF CLOZAPINE WITH A FATTY ACID AND ITS USE FOR TREATING SCHIZOPHRENIA LUITPOLD PHARM INC (US) 2005-05-25 EP claimed
US-11389453-B2 Compositions and methods for treating chemosensory dysfunction CYRANO THERAPEUTICS, INC. (US) 2022-07-19 US disclosed
EP-1931320-B1 MICROPARTICLES WITH MODIFIED RELEASE OF AT LEAST ONE ACTIVE PRINCIPLE AND ORAL DOSAGE FORM COMPRISING THE SAME FLAMEL IRELAND LTD (IE) 2022-06-15 EP disclosed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed
US-11191719-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2021-12-07 US disclosed
WO-2003011255-A1 GASTRIC RETENTION CONTROLLED DRUG DELIVERY SYSTEM SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2003-02-13 WO disclosed
WO-2002045693-A1 PHARMACEUTICAL PREPARATION COMPRISING AN ACTIVE DISPERSED ON A MATRIX ALTANA PHARMA AG (DE) 2002-06-13 WO disclosed
EP-1163011-A2 FATTY ACID-ANTICANCER CONJUGATES AND USES THEREOF Protarga Inc. (US) 2001-12-19 EP disclosed
WO-2000053231-A2 FATTY ACID-ANTICANCER CONJUGATES AND USES THEREOF PROTARGA, INC. (US) 2000-09-14 WO disclosed
CN-1152941-A Genes for synthesizing antipathogenic substances CIBA GEIGY AG (CH) 1997-06-25 CN disclosed