Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARK7 | Q99497 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | JUN | P05412 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16650230 | 0.81 | PARK7 (0.42) | PARK7 | |
| SCHEMBL353155 | 0.77 | PARK7 (0.48) | PARK7JUNNFKB1NFKB2RELA | |
| SCHEMBL352102 | 0.76 | PARK7 (0.47) | PARK7 | |
| SCHEMBL352808 | 0.75 | PARK7 (0.46) | PARK7 | |
| SCHEMBL115782 | 0.75 | PARK7 (0.51) | PARK7 | |
| SCHEMBL351849 | 0.75 | PARK7 (0.45) | PARK7 | |
| Dehydroxymethylepoxyquinomicin SCHEMBL1671089 | 0.74 | PARK7 (0.54) | PARK7NFKB1NFKB2RELA | |
| SCHEMBL353742 | 0.73 | PARK7 (0.54) | PARK7NFKB1NFKB2RELA | |
| SCHEMBL666087 | 0.73 | PARK7 (0.64) | PARK7 | |
| SCHEMBL352443 | 0.72 | PARK7 (0.43) | PARK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120015952-A1 | Inhibitors of NF-KB | PROFECTUS BIOSCIENCES, INC. (US) | 2012-01-19 | — | — | US | claimed |
| US-20120015952-A1 | Inhibitors of NF-KB | PROFECTUS BIOSCIENCES, INC. (US) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015952-A1 | Inhibitors of NF-KB | NFKBIA, IKBKB, IKBKG | PARK7 3327/4885GRM5 4441/4885JUN 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.