Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8670042 | 0.89 | THRB (0.43) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL3517115 | 0.88 | TDP1 (0.44) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL15361902 | 0.85 | TDP1 (0.46) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL9715816 | 0.84 | TDP1 (0.45) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL15361896 | 0.81 | TSHR (0.46) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL2345681 | 0.81 | THRB (0.43) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL27637386 | 0.78 | TSHR (0.54) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL1782446 | 0.78 | POLB (0.44) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL15361829 | 0.76 | TSHR (0.44) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL28355460 | 0.75 | TDP1 (0.41) | TDP1POLBAPEX1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665252-B1 | Two-pack aqueous coating composition | KANSAI PAINT CO LTD (JP) | 1998-12-16 | — | — | EP | claimed |
| US-5519089-A | ALKOXYSILANE CONTAINING ACRYLIC COPOLYMER AND POLYISOCYANATE | KANSAI PAINT CO., LTD. (JP) | 1996-05-21 | — | — | US | claimed |
| EP-0665252-A2 | Two-pack aqueous coating composition | KANSAI PAINT CO., LTD. (JP) | 1995-08-02 | — | — | EP | claimed |
| EP-0665252-B1 | Two-pack aqueous coating composition | KANSAI PAINT CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5519089-A | ALKOXYSILANE CONTAINING ACRYLIC COPOLYMER AND POLYISOCYANATE | KANSAI PAINT CO., LTD. (JP) | 1996-05-21 | — | — | US | disclosed |
| EP-0665252-A2 | Two-pack aqueous coating composition | KANSAI PAINT CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |