SCHEMBL3517343

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17047668	0.69	HSD17B10 (0.54)	TDP1L3MBTL1POLBNPC1RAB9A
	SCHEMBL3517549	0.69	TDP1 (0.45)	TDP1CYP2C9L3MBTL1POLBNPC1
	SCHEMBL29261700	0.69	KDM4E (0.42)	TDP1POLBNPC1RAB9AALDH1A1
	SCHEMBL409136	0.67	TDP1 (0.38)	TDP1L3MBTL1POLBRAB9AALDH1A1
	SCHEMBL8307380	0.66	TDP1 (0.40)	TDP1L3MBTL1POLBNPC1RAB9A
	SCHEMBL14100096	0.66	TDP1 (0.71)	TDP1CYP2C9L3MBTL1POLBNPC1
	SCHEMBL28145280	0.66	ALDH1A1 (0.39)	TDP1L3MBTL1POLBNPC1RAB9A
	SCHEMBL8600943	0.66	TDP1 (0.71)	TDP1CYP2C9L3MBTL1POLBNPC1
	SCHEMBL1133466	0.66	TDP1 (0.66)	TDP1CYP2C9L3MBTL1POLBNPC1
	SCHEMBL15547050	0.65	TDP1 (0.55)	TDP1CYP2C9L3MBTL1POLBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.