SCHEMBL409136

SCHEMBL409136

O=c1cc[nH]c(=O)n1-c1nccs1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.38
ALDH1A1 P00352 4/20 0.38
KDM4E B2RXH2 3/20 0.38
GAA P10253 3/20 0.38
MAPT P10636 3/20 0.38
HSD17B10 Q99714 1/20 0.38
G6PD P11413 1/20 0.38
PKM P14618 1/20 0.38
MPI P34949 1/20 0.38
EP300 Q09472 1/20 0.38
KAT2A Q92830 1/20 0.38
KAT2B Q92831 1/20 0.38
SLC11A2 P49281 1/20 0.37
KMT2A Q03164 4/20 0.36
MEN1 O00255 3/20 0.36
HPGD P15428 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36
RECQL P46063 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8115803 0.72 SLC11A2 (0.48) TDP1ALDH1A1KDM4EGAAMAPT
SCHEMBL4662854 0.69 ALDH1A1 (0.32) ALDH1A1KMT2AHPGD
SCHEMBL4172313 0.67 CDK5 (0.50) TDP1ALDH1A1KDM4EGAAMAPT
SCHEMBL3517343 0.67 TDP1 (0.46) TDP1ALDH1A1KDM4EGAAHSD17B10
SCHEMBL8310458 0.66 KDM4E (0.48) TDP1ALDH1A1KDM4EMAPTHSD17B10
SCHEMBL5289093 0.66 TNF (0.32)
SCHEMBL11896422 0.65 KDM4E (0.42) TDP1ALDH1A1KDM4EMAPTSLC11A2
SCHEMBL16657365 0.65 DAO (0.41) TDP1ALDH1A1KDM4EGAAMAPT
SCHEMBL31205780 0.65 KDM4E (0.46) TDP1ALDH1A1KDM4EGAAMAPT
SCHEMBL29261700 0.65 KDM4E (0.42) TDP1ALDH1A1KDM4EGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080044425-A1 POLYPEPTIDES HAVING PHOSPHOLIPASE A2 ACTIVITY KYOWA HAKKO KOGYO CO., LTD. (JP) 2008-02-21 US claimed
US-20080015165-A1 NOVEL POLYPEPTIDE KYOWA HAKKO KOGYO CO., LTD. (JP) 2008-01-17 US claimed
US-7291491-B2 Having poly-N-acetyllactosamine sugar chains synthesis-related activity; use in antiinflammation, antiinfection, inhibition of cancer metastasis KYOWA HAKKO KOGYO CO., LTD. (JP) 2007-11-06 US claimed
US-20040014089-A1 Polypeptides having phospholipase a2 activity KYOWA HAKKO KIRIN CO., LTD. (JP) 2004-01-22 US claimed
US-20030166208-A1 Novel polypeptides KYOWA HAKKO KOGYO CO., LTD. (JP) 2003-09-04 US claimed
EP-1329511-A1 POLYPEPTIDE HAVING PHOSPHOLIPASE A2 ACTIIVTY KYOWA HAKKO KOGYO CO., LTD. (JP) 2003-07-23 EP claimed
EP-1162269-A1 NOVEL POLYPEPTIDE KYOWA HAKKO KOGYO CO., LTD. (JP) 2001-12-12 EP claimed
EP-1103604-A1 NOVEL POLYPEPTIDE KYOWA HAKKO KOGYO CO., LTD. (JP) 2001-05-30 EP claimed
WO-1999052906-A1 SUBSTITUTED OXAZOLYLE AND THIAZOLYL URACIL HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1999-10-21 WO claimed
EP-0937775-A2 Beta 1,3-N-acetylglucosaminyltransferase, DNA encoding it and its use KYOWA HAKKO KOGYO CO., LTD. (JP) 1999-08-25 EP claimed
CN-114828891-A Treatment of diabetes targeting abnormal stem cells 比奥兹普科德公司 2022-07-29 CN disclosed
CN-114828890-A Treatment of diabetes with stem cell migration agent 比奥兹普科德公司 2022-07-29 CN disclosed
CN-114761044-A Nucleic acid constructs encoding chimeric rhodopsins 锐视维公司 2022-07-15 CN disclosed
CN-113395976-A Preventive or therapeutic agent for benign tumor 株式会社癌免疫研究所 2021-09-14 CN disclosed
CN-112654708-A Novel lipase for decomposing trans-fatty acid-containing oil 国立大学法人东海国立大学机构 2021-04-13 CN disclosed
EP-1329511-A1 POLYPEPTIDE HAVING PHOSPHOLIPASE A2 ACTIIVTY KYOWA HAKKO KOGYO CO., LTD. (JP) 2003-07-23 EP disclosed
EP-1162269-A1 NOVEL POLYPEPTIDE KYOWA HAKKO KOGYO CO., LTD. (JP) 2001-12-12 EP disclosed
EP-1103604-A1 NOVEL POLYPEPTIDE KYOWA HAKKO KOGYO CO., LTD. (JP) 2001-05-30 EP disclosed
WO-1999052906-A1 SUBSTITUTED OXAZOLYLE AND THIAZOLYL URACIL HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1999-10-21 WO disclosed
WO-1999052906-A1 SUBSTITUTED OXAZOLYLE AND THIAZOLYL URACIL HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1999-10-21 WO disclosed