Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.30 |
| ▸ | WNT3A | P56704 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL351218 | 0.77 | GPR3 (0.33) | GPR3NOTUM | |
| SCHEMBL350611 | 0.77 | GPR3 (0.33) | GPR3NOTUM | |
| SCHEMBL1096709 | 0.77 | GPR3 (0.33) | GPR3NOTUM | |
| SCHEMBL349055 | 0.72 | P4HB (0.30) | GPR3 | |
| SCHEMBL16026307 | 0.71 | GPR3 (0.31) | GPR3 | |
| SCHEMBL350075 | 0.67 | — | — | |
| SCHEMBL789550 | 0.67 | CYP3A4 (0.35) | — | |
| SCHEMBL1752066 | 0.64 | AHR (0.48) | GPR3NOTUMCTNNB1WNT3A | |
| SCHEMBL8239476 | 0.64 | TSHR (0.39) | GPR3NOTUMCTNNB1WNT3A | |
| SCHEMBL939408 | 0.64 | GPR3 (0.38) | GPR3NOTUMCTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120015981-A1 | Active compound combinations | BAYER CORPSCIENCE AG (DE) | 2012-01-19 | — | — | US | disclosed |
| EP-2391214-A1 | ACTIVE COMPOUND COMBINATIONS | Bayer CropScience AG (DE) | 2011-12-07 | — | — | EP | disclosed |
| EP-2391213-A1 | ACTIVE COMPOUND COMBINATIONS | Bayer CropScience AG (DE) | 2011-12-07 | — | — | EP | disclosed |
| US-20110294855-A1 | Active Compound Combinations | BAYER CROPSCIENCE AG (DE) | 2011-12-01 | — | — | US | disclosed |
| WO-2010086120-A1 | ACTIVE COMPOUND COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2010-08-05 | — | — | WO | disclosed |
| WO-2010086109-A1 | ACTIVE COMPOUND COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2010-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294855-A1 | Active Compound Combinations | PFAS, AFF1, AFF2 | GPR3 1447/4885NOTUM 45/4885CTNNB1 3767/4885 |
| US-20120015981-A1 | Active compound combinations | PFAS, CBR3, AADAC | GPR3 2154/4885NOTUM 23/4885CTNNB1 3985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.