Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4277314 | 0.84 | ALDH1A1 (0.62) | ALDH1A1HPGDALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL28062794 | 0.84 | ALDH1A1 (0.62) | ALDH1A1HPGDALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL851358 | 0.81 | ALDH1A1 (0.69) | ALDH1A1HPGDALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL29540343 | 0.81 | ALDH1A1 (0.69) | ALDH1A1HPGDALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL27347353 | 0.80 | ALDH1A1 (0.74) | ALDH1A1HPGDALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL28065953 | 0.80 | ALDH1A1 (0.57) | ALDH1A1HPGDALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL724711 | 0.80 | ALDH1A1 (0.62) | ALDH1A1HPGDALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL15111907 | 0.80 | ALDH1A1 (0.57) | ALDH1A1HPGDALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL38658780 | 0.80 | ALDH1A1 (0.57) | ALDH1A1HPGDALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL30494127 | 0.80 | ALDH1A1 (0.62) | ALDH1A1HPGDALOX15HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2227770-A2 | PROLYL HYDROXYLASE INHIBITORS | GlaxoSmithKline LLC (US) | 2010-09-15 | — | — | EP | disclosed |
| WO-2009073497-A2 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-11 | — | — | WO | disclosed |
| CN-100441585-C | Rhodium and iridium complexes | COVION ORGANIC SEMICONDUCTORS (DE) | 2008-12-10 | — | — | CN | disclosed |
| CN-1500093-A | Rhodium and iridium complexes | �����л��뵼������˾ | 2004-05-26 | — | — | CN | disclosed |