Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.56 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29540343 | 1.00 | ALDH1A1 (0.69) | ALDH1A1HPGDALOX15HSD17B10RAB9A | |
| Hydrochloric Acid SCHEMBL29488564 | 0.98 | ALDH1A1 (0.67) | ALDH1A1HPGDALOX15HSD17B10RAB9A | |
| Trifluoroacetic Acid SCHEMBL5480884 | 0.88 | ALDH1A1 (0.60) | ALDH1A1HPGDALOX15HSD17B10RAB9A | |
| Trifluoroacetic Acid SCHEMBL30643070 | 0.88 | ALDH1A1 (0.60) | ALDH1A1HPGDALOX15HSD17B10RAB9A | |
| Cinnoline SCHEMBL5471704 | 0.84 | ALDH1A1 (0.51) | ALDH1A1HPGDALOX15HSD17B10RAB9A | |
| SCHEMBL27347353 | 0.83 | ALDH1A1 (0.74) | ALDH1A1HPGDALOX15HSD17B10RAB9A | |
| SCHEMBL354679 | 0.82 | ALDH1A1 (1.00) | ALDH1A1HPGDALOX15HSD17B10RAB9A | |
| SCHEMBL5358823 | 0.82 | ALDH1A1 (0.71) | ALDH1A1HPGDALOX15HSD17B10RAB9A | |
| SCHEMBL29623278 | 0.82 | ALDH1A1 (1.00) | ALDH1A1HPGDALOX15HSD17B10RAB9A | |
| SCHEMBL3518633 | 0.81 | ALDH1A1 (0.65) | ALDH1A1HPGDALOX15HSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 386 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3384007-B1 | IMPROVED METHODS FOR REPROGRAMING NON-PLURIPOTENT CELLS INTO PLURIPOTENT STEM CELLS | BEIHAO STEM CELL AND REGENERATIVE MEDICINE RES INSTITUTE CO LTD (CN) | 2024-03-27 | — | — | EP | claimed |
| CN-117751107-A | Organic pyridine-pyrazole compounds and uses thereof | 博善人工智能剑桥有限公司 | 2024-03-22 | — | — | CN | claimed |
| EP-3019596-B1 | COMPOSITIONS AND METHODS FOR REPROGRAMING NON- PLURIPOTENT CELLS INTO PLURIPOTENT STEM CELLS | HONG GUAN LTD (CN) | 2023-07-05 | — | — | EP | claimed |
| CN-116256450-A | Method for distinguishing acerola cherry fruit powder from acerola cherry juice powder and screening method of characteristic markers of acerola cherry fruit powder | 中国农业科学院农业质量标准与检测技术研究所 | 2023-06-13 | — | — | CN | claimed |
| US-20230133600-A1 | PHARMACEUTICAL USE OF KETOAMIDE-BASED COMPOUND | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2023-05-04 | — | — | US | claimed |
| EP-3613735-B1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | NAT UNIV PUSAN IND UNIV COOP FOUND (KR) | 2023-04-12 | — | — | EP | claimed |
| EP-4098258-A1 | PHARMACEUTICAL USE OF KETOAMIDE-BASED COMPOUND | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2022-12-07 | — | — | EP | claimed |
| WO-2022249113-A1 | NOVEL COMPOUND INHIBITING BINDING BETWEEN AIMP2-DX2 AND KRAS, AND USE THEREOF | 주식회사 자이메디 | 2022-12-01 | — | — | WO | claimed |
| CN-110698418-B | 3-arylamino quinoxaline-2-formamide derivative and preparation method and application thereof | 广西师范大学 | 2022-07-01 | — | — | CN | claimed |
| US-20220112177-A1 | KETOAMIDE COMPOUND AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | FUDAN UNIVERSITY (CN) | 2022-04-14 | — | — | US | claimed |
| CN-1789246-A | Metabotropic glutamate receptor antagonists and their use for treating central nervous system diseases | NPS PHARMA INC (US) | 2006-06-21 | — | — | CN | claimed |
| CN-1590378-A | Quinoxaline derivative and preparation method and application thereof | SHANGHAI INST MATERIA MEDICA (CN) | 2005-03-09 | — | — | CN | claimed |
| CN-1554649-A | Metabotropic glutamate receptor antagonists for treating central nervous system diseases | NPSҩ������˾ | 2004-12-15 | — | — | CN | claimed |
| EP-1202734-A4 | 3(5)-UREIDO-PYRAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA ITALIA SPA (IT) | 2004-09-01 | — | — | EP | claimed |
| US-6642347-B1 | Bismaleimide polymerization initiators; increasing toughness of thermosets | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE | 2003-11-04 | — | — | US | claimed |
| JP-2003507328-A | — | — | 2003-02-25 | — | — | JP | claimed |
| CN-1361768-A | Metabotropic glutamate receptor antagonists and their use for treating central nervous system disorders | NPS PHARMA INC (US) | 2002-07-31 | — | — | CN | claimed |
| EP-1202734-A1 | 3(5)-UREIDO-PYRAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR AGENTS | Pharmacia Italia S.p.A. (IT) | 2002-05-08 | — | — | EP | claimed |
| CN-1285820-A | Metabotropic glutamate receptor antagonists for the treatment of central nervous system disorders | NPS PHARMA INC (US) | 2001-02-28 | — | — | CN | claimed |
| WO-2001012188-A1 | 3(5)-UREIDO-PYRAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2001-02-22 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220112177-A1 | KETOAMIDE COMPOUND AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | ACE, REN, ACE2 | ALDH1A1 1463/4885HPGD 1068/4885ALOX15 720/4885 |
| US-20230133600-A1 | PHARMACEUTICAL USE OF KETOAMIDE-BASED COMPOUND | CTSL, CTSV, CTSS | ALDH1A1 2113/4885HPGD 1413/4885ALOX15 796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.