Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MDM4 | O15151 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3305044 | 0.96 | HCAR2 (0.38) | MAPTATMHCAR2AKR1B10AKR1B1 | |
| SCHEMBL9402866 | 0.92 | MAPT (0.39) | MAPTHCAR2AKR1B10AKR1B1ALOX5 | |
| SCHEMBL9402872 | 0.91 | ATM (0.40) | ATMHCAR2AKR1B10AKR1B1APP | |
| SCHEMBL9402709 | 0.90 | ATM (0.45) | MAPTATMHCAR2APPNPC1 | |
| SCHEMBL3307221 | 0.88 | HCAR2 (0.40) | ATMHCAR2AKR1B10AKR1B1APP | |
| SCHEMBL3517113 | 0.87 | ALOX5 (0.39) | ATMHCAR2AKR1B10AKR1B1ALOX5 | |
| SCHEMBL1067387 | 0.86 | THRB (0.47) | MAPTNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL27710245 | 0.85 | HCAR2 (0.40) | MAPTHCAR2AKR1B10AKR1B1ALOX5 | |
| SCHEMBL9402868 | 0.84 | ATM (0.43) | MAPTATMHCAR2APPNPC1 | |
| SCHEMBL3310444 | 0.83 | KDM4E (0.39) | ATMHCAR2AKR1B10AKR1B1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2228362-B1 | 4-HYDROXYPHENYLALKYLAMINE DERIVATIVE | DOW CORNING TORAY CO LTD (JP) | 2017-06-07 | — | — | EP | disclosed |
| EP-2228362-A1 | 4-HYDROXYPHENYLALKYLAMINE DERIVATIVE | Dow Corning Toray Co., Ltd. (JP) | 2010-09-15 | — | — | EP | disclosed |
| US-5332779-A | Polymerizable silica sol, adamantane derivative for use in the sol and cured resin prepared using the same | KAWASAKI STEEL CORPORATION (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0460560-A2 | Polymerizable silica sol, adamantane derivative for use in the sol and cured resin prepared using the same | KAWASAKI STEEL CORPORATION (JP) | 1991-12-11 | — | — | EP | disclosed |