Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.39 |
| ▸ | APP | P05067 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3307221 | 0.96 | HCAR2 (0.40) | ATMHCAR2APPLMNANPC1 | |
| SCHEMBL9402709 | 0.94 | ATM (0.45) | ATMHCAR2APPLMNANPC1 | |
| SCHEMBL9402750 | 0.92 | HCAR2 (0.40) | ATMHCAR2APPLMNAAKR1B10 | |
| SCHEMBL3519508 | 0.91 | MAPT (0.38) | ATMHCAR2APPLMNANPC1 | |
| SCHEMBL3305044 | 0.88 | HCAR2 (0.38) | ATMHCAR2APPLMNANPC1 | |
| SCHEMBL9402868 | 0.88 | ATM (0.43) | ATMHCAR2APPLMNANPC1 | |
| SCHEMBL1063249 | 0.86 | TSHR (0.49) | ATMHCAR2LMNANPC1RAB9A | |
| SCHEMBL3517113 | 0.86 | ALOX5 (0.39) | ATMHCAR2AKR1B10AKR1B1TDP1 | |
| SCHEMBL9402866 | 0.83 | MAPT (0.39) | HCAR2LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7873872 | 0.82 | TSHR (0.48) | HCAR2LMNANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332779-A | Polymerizable silica sol, adamantane derivative for use in the sol and cured resin prepared using the same | KAWASAKI STEEL CORPORATION (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0460560-A2 | Polymerizable silica sol, adamantane derivative for use in the sol and cured resin prepared using the same | KAWASAKI STEEL CORPORATION (JP) | 1991-12-11 | — | — | EP | disclosed |