Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 12/20 | 0.55 |
| ▸ | MAOA | P21397 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 2/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5225323 | 0.91 | PGR (0.65) | PGRKMT2ATDP2 | |
| SCHEMBL3522216 | 0.86 | PGR (0.63) | PGRKMT2A | |
| SCHEMBL3521129 | 0.83 | MAOA (0.71) | PGRMAOAMAOBTGM2CES1 | |
| SCHEMBL9098061 | 0.78 | KMT2A (0.61) | PGRMAOAMAOBKMT2ATDP2 | |
| SCHEMBL24270339 | 0.72 | KMT2A (0.78) | PGRKMT2A | |
| SCHEMBL5337809 | 0.71 | GAA (0.62) | PGRKMT2A | |
| SCHEMBL4370977 | 0.70 | CES1 (0.73) | MAOAMAOBTGM2CES1TDP2 | |
| SCHEMBL3521399 | 0.70 | PGR (1.00) | PGRMAOBPDE3BPDE3A | |
| Ammonia Solution, Strong SCHEMBL27558922 | 0.69 | PGR (0.97) | PGRMAOBPDE3BPDE3A | |
| SCHEMBL2789935 | 0.69 | MAOA (1.00) | MAOAMAOBKMT2ATGM2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645761-B2 | Indoline derivatives | WYETH (US) | 2010-01-12 | — | — | US | disclosed |