SCHEMBL3520487

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14188805	0.90	KDM4E (0.41)	KDM4ELMNAPKMADORA1ADORA3
	SCHEMBL14188810	0.84	NPC1 (0.45)	KDM4ELMNAPKMSMN1; SMN2ALDH1A1
	SCHEMBL14188813	0.84	TSHR (0.40)	KDM4ELMNAPKMADORA1ADORA3
	SCHEMBL12713296	0.83	KDM4E (0.49)	KDM4ELMNAPKMADORA1ADORA3
	SCHEMBL203832	0.81	KDM4E (0.48)	KDM4ELMNAPKMADORA1ADORA3
	SCHEMBL201295	0.81	LMNA (0.51)	KDM4ELMNAPKMADORA1ADORA3
	SCHEMBL3507658	0.81	KDM4E (0.51)	KDM4ELMNAPKMADORA1ADORA3
	SCHEMBL12509518	0.80	KDM4E (0.47)	KDM4ELMNAPKMADORA1ADORA3
	SCHEMBL12024804	0.80	KDM4E (0.47)	KDM4ELMNAPKMADORA1ADORA3
	SCHEMBL416916	0.80	KDM4E (0.61)	KDM4ELMNAPKMADORA1ADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.