Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 4/20 | 0.64 |
| ▸ | RAD52 | P43351 | 5/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | POLR1A | O95602 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | UHRF1 | Q96T88 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13520610 | 0.90 | TERT (0.57) | TERTRAD52MEN1MITFPOLB | |
| SCHEMBL3293187 | 0.88 | TERT (0.55) | TERTRAD52MEN1MITFPOLB | |
| SCHEMBL3517478 | 0.87 | TERT (0.49) | TERTRAD52MEN1MITFPOLB | |
| SCHEMBL3290737 | 0.83 | BCHE (0.46) | TERTMEN1POLBKMT2A | |
| SCHEMBL13338303 | 0.83 | MEN1 (0.49) | TERTMEN1POLBKMT2AALDH1A1 | |
| SCHEMBL3520973 | 0.83 | TERT (0.47) | TERTMEN1POLBKMT2APOLR1A | |
| SCHEMBL3293980 | 0.81 | TERT (0.49) | TERTKDM4E | |
| SCHEMBL29196428 | 0.81 | TERT (0.54) | TERTMEN1POLBKMT2AALDH1A1 | |
| SCHEMBL3292099 | 0.80 | TP53 (0.61) | TERTMEN1POLBKMT2AHTT | |
| SCHEMBL3518638 | 0.80 | TERT (0.47) | TERTMEN1POLBKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331355-A1 | Substituted Quinolines for the Treatment of Cancer | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331355-A1 | Substituted Quinolines for the Treatment of Cancer | TOP2B, TOP1, TOP2A | TERT 1447/4885RAD52 198/4885HTR2C 464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.