Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | POLR1A | O95602 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3520767 | 0.83 | TERT (0.64) | TERTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL13520610 | 0.82 | TERT (0.57) | TERTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL13338303 | 0.81 | MEN1 (0.49) | TERTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL3293187 | 0.80 | TERT (0.55) | TERTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL29196428 | 0.79 | TERT (0.54) | TERTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL12177588 | 0.77 | TERT (0.48) | TERTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL3517478 | 0.77 | TERT (0.49) | TERTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL13338301 | 0.77 | TERT (0.48) | TERTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL3293980 | 0.75 | TERT (0.49) | TERTKDM4ELMNAUSP2 | |
| SCHEMBL9390934 | 0.75 | TERT (0.51) | TERTKDM4ESMN1; SMN2LMNADYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331355-A1 | Substituted Quinolines for the Treatment of Cancer | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331355-A1 | Substituted Quinolines for the Treatment of Cancer | TOP2B, TOP1, TOP2A | TERT 1447/4885KMT2A 2452/4885MEN1 3062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.