Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 3/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7953412 | 0.79 | CHRNA7 (0.37) | — | |
| Hydrochloric Acid SCHEMBL10345271 | 0.78 | CHRNA7 (0.37) | — | |
| SCHEMBL3443178 | 0.76 | TACR1 (0.40) | MMP2MMP14MMP13 | |
| SCHEMBL27286007 | 0.71 | PTGS2 (0.42) | ADAM17PTGS2PTGS1TRPM8TRPV4 | |
| SCHEMBL23089342 | 0.67 | SLC6A2 (0.33) | — | |
| SCHEMBL13353146 | 0.67 | MMP1 (0.47) | ADAM17MMP2MMP14MMP13 | |
| SCHEMBL29813091 | 0.67 | GPR119 (0.37) | PTGS2PTGS1GPR119MMP13 | |
| SCHEMBL29812829 | 0.67 | GPR119 (0.37) | PTGS2PTGS1GPR119MMP13 | |
| SCHEMBL26966943 | 0.67 | GPR119 (0.37) | PTGS2PTGS1GPR119MMP13 | |
| SCHEMBL29128279 | 0.66 | MAP2K1 (0.51) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4294800-B1 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS INC (US) | 2026-05-06 | — | — | EP | disclosed |