⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30911399 | 0.85 | — | — | |
| SCHEMBL35210853 | 0.77 | NT5E (0.33) | — | |
| SCHEMBL35211263 | 0.77 | NT5E (0.33) | — | |
| SCHEMBL30911367 | 0.74 | CYP3A4 (0.31) | — | |
| SCHEMBL30911387 | 0.68 | NT5E (0.34) | — | |
| SCHEMBL24136995 | 0.64 | HEXA (0.34) | — | |
| SCHEMBL28302657 | 0.64 | GABRB3 (0.33) | — | |
| SCHEMBL35211471 | 0.64 | TRPA1 (0.41) | — | |
| SCHEMBL3062694 | 0.63 | HSP90AA1 (0.43) | — | |
| SCHEMBL20488776 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125375-A1 | SUBSTITUTED 1H-PYRAZOLO-PYRIDINE AND -PYRIMIDINE COMPOUNDS | PFIZER INC. (US) | 2026-05-07 | — | — | US | disclosed |